Brahimi F - Search Results

1

Vaccination with Tumor-Ganglioside Glycomimetics Activates a Selective Immunity that Affords Cancer Therapy.

Tong W, Maira M, Roychoudhury R, Galan A, Brahimi F, Gilbert M, Cunningham AM, Josephy S, Pirvulescu I, Moffett S, Saragovi HU. Tong W, et al. Among authors: brahimi f. Cell Chem Biol. 2019 Jul 18;26(7):1013-1026.e4. doi: 10.1016/j.chembiol.2019.03.018. Epub 2019 May 16. Cell Chem Biol. 2019. PMID: 31105061 Free article.

2

A combinatorial method for solution-phase synthesis of labeled bivalent beta-turn mimics.

Angell Y, Chen D, Brahimi F, Saragovi HU, Burgess K. Angell Y, et al. Among authors: brahimi f. J Am Chem Soc. 2008 Jan 16;130(2):556-65. doi: 10.1021/ja074717z. Epub 2007 Dec 19. J Am Chem Soc. 2008. PMID: 18088119

3

A peptidomimetic of NT-3 acts as a TrkC antagonist.

Brahimi F, Malakhov A, Lee HB, Pattarawarapan M, Ivanisevic L, Burgess K, Saragovi HU. Brahimi F, et al. Peptides. 2009 Oct;30(10):1833-9. doi: 10.1016/j.peptides.2009.07.015. Epub 2009 Jul 30. Peptides. 2009. PMID: 19647025 Free PMC article.

4

Bivalent peptidomimetic ligands of TrkC are biased agonists and selectively induce neuritogenesis or potentiate neurotrophin-3 trophic signals.

Chen D, Brahimi F, Angell Y, Li YC, Moscowicz J, Saragovi HU, Burgess K. Chen D, et al. Among authors: brahimi f. ACS Chem Biol. 2009 Sep 18;4(9):769-81. doi: 10.1021/cb9001415. ACS Chem Biol. 2009. PMID: 19735123 Free PMC article.

5

An agonistic TrkB mAb causes sustained TrkB activation, delays RGC death, and protects the retinal structure in optic nerve axotomy and in glaucoma.

Bai Y, Xu J, Brahimi F, Zhuo Y, Sarunic MV, Saragovi HU. Bai Y, et al. Among authors: brahimi f. Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4722-31. doi: 10.1167/iovs.09-5032. Epub 2010 Mar 31. Invest Ophthalmol Vis Sci. 2010. PMID: 20357199

6

Bivalent diketopiperazine-based tropomysin receptor kinase C (TrkC) antagonists.

Liu J, Brahimi F, Saragovi HU, Burgess K. Liu J, et al. Among authors: brahimi f. J Med Chem. 2010 Jul 8;53(13):5044-8. doi: 10.1021/jm100148d. J Med Chem. 2010. PMID: 20540510 Free PMC article.

7

A monovalent agonist of TrkA tyrosine kinase receptors can be converted into a bivalent antagonist.

Brahimi F, Liu J, Malakhov A, Chowdhury S, Purisima EO, Ivanisevic L, Caron A, Burgess K, Saragovi HU. Brahimi F, et al. Biochim Biophys Acta. 2010 Sep;1800(9):1018-26. doi: 10.1016/j.bbagen.2010.06.007. Epub 2010 Jun 19. Biochim Biophys Acta. 2010. PMID: 20600627 Free PMC article.

8

Ligand-dependent TrkA activity in brain differentially affects spatial learning and long-term memory.

Aboulkassim T, Tong XK, Tse YC, Wong TP, Woo SB, Neet KE, Brahimi F, Hamel E, Saragovi HU. Aboulkassim T, et al. Among authors: brahimi f. Mol Pharmacol. 2011 Sep;80(3):498-508. doi: 10.1124/mol.111.071332. Epub 2011 May 26. Mol Pharmacol. 2011. PMID: 21616921

9

Combinatorial assembly of small molecules into bivalent antagonists of TrkC or TrkA receptors.

Brahimi F, Ko E, Malakhov A, Burgess K, Saragovi HU. Brahimi F, et al. PLoS One. 2014 Mar 6;9(3):e89617. doi: 10.1371/journal.pone.0089617. eCollection 2014. PLoS One. 2014. PMID: 24603864 Free PMC article.

10

The Paradoxical Signals of Two TrkC Receptor Isoforms Supports a Rationale for Novel Therapeutic Strategies in ALS.

Brahimi F, Maira M, Barcelona PF, Galan A, Aboulkassim T, Teske K, Rogers ML, Bertram L, Wang J, Yousefi M, Rush R, Fabian M, Cashman N, Saragovi HU. Brahimi F, et al. PLoS One. 2016 Oct 3;11(10):e0162307. doi: 10.1371/journal.pone.0162307. eCollection 2016. PLoS One. 2016. PMID: 27695040 Free PMC article.

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