Saragovi HU - Search Results

1

Vaccination with Tumor-Ganglioside Glycomimetics Activates a Selective Immunity that Affords Cancer Therapy.

Tong W, Maira M, Roychoudhury R, Galan A, Brahimi F, Gilbert M, Cunningham AM, Josephy S, Pirvulescu I, Moffett S, Saragovi HU. Tong W, et al. Among authors: saragovi hu. Cell Chem Biol. 2019 Jul 18;26(7):1013-1026.e4. doi: 10.1016/j.chembiol.2019.03.018. Epub 2019 May 16. Cell Chem Biol. 2019. PMID: 31105061 Free article.

2

A combinatorial method for solution-phase synthesis of labeled bivalent beta-turn mimics.

Angell Y, Chen D, Brahimi F, Saragovi HU, Burgess K. Angell Y, et al. Among authors: saragovi hu. J Am Chem Soc. 2008 Jan 16;130(2):556-65. doi: 10.1021/ja074717z. Epub 2007 Dec 19. J Am Chem Soc. 2008. PMID: 18088119

3

Preparation and characterization of new anti-PSMA monoclonal antibodies with potential clinical use.

Moffett S, Mélançon D, DeCrescenzo G, St-Pierre C, Deschénes F, Saragovi HU, Gold P, Cuello AC. Moffett S, et al. Among authors: saragovi hu. Hybridoma (Larchmt). 2007 Dec;26(6):363-72. doi: 10.1089/hyb.2007.0522. Hybridoma (Larchmt). 2007. PMID: 18158780

4

A peptidomimetic of NT-3 acts as a TrkC antagonist.

Brahimi F, Malakhov A, Lee HB, Pattarawarapan M, Ivanisevic L, Burgess K, Saragovi HU. Brahimi F, et al. Among authors: saragovi hu. Peptides. 2009 Oct;30(10):1833-9. doi: 10.1016/j.peptides.2009.07.015. Epub 2009 Jul 30. Peptides. 2009. PMID: 19647025 Free PMC article.

5

Bivalent peptidomimetic ligands of TrkC are biased agonists and selectively induce neuritogenesis or potentiate neurotrophin-3 trophic signals.

Chen D, Brahimi F, Angell Y, Li YC, Moscowicz J, Saragovi HU, Burgess K. Chen D, et al. Among authors: saragovi hu. ACS Chem Biol. 2009 Sep 18;4(9):769-81. doi: 10.1021/cb9001415. ACS Chem Biol. 2009. PMID: 19735123 Free PMC article.

6

Small-molecule ligands of GD2 ganglioside, designed from NMR studies, exhibit induced-fit binding and bioactivity.

Tong W, Gagnon M, Sprules T, Gilbert M, Chowdhury S, Meerovitch K, Hansford K, Purisima EO, Blankenship JW, Cheung NK, Gehring K, Lubell WD, Saragovi HU. Tong W, et al. Among authors: saragovi hu. Chem Biol. 2010 Feb 26;17(2):183-94. doi: 10.1016/j.chembiol.2010.01.012. Chem Biol. 2010. PMID: 20189108

7

An agonistic TrkB mAb causes sustained TrkB activation, delays RGC death, and protects the retinal structure in optic nerve axotomy and in glaucoma.

Bai Y, Xu J, Brahimi F, Zhuo Y, Sarunic MV, Saragovi HU. Bai Y, et al. Among authors: saragovi hu. Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4722-31. doi: 10.1167/iovs.09-5032. Epub 2010 Mar 31. Invest Ophthalmol Vis Sci. 2010. PMID: 20357199

8

Bivalent diketopiperazine-based tropomysin receptor kinase C (TrkC) antagonists.

Liu J, Brahimi F, Saragovi HU, Burgess K. Liu J, et al. Among authors: saragovi hu. J Med Chem. 2010 Jul 8;53(13):5044-8. doi: 10.1021/jm100148d. J Med Chem. 2010. PMID: 20540510 Free PMC article.

9

A monovalent agonist of TrkA tyrosine kinase receptors can be converted into a bivalent antagonist.

Brahimi F, Liu J, Malakhov A, Chowdhury S, Purisima EO, Ivanisevic L, Caron A, Burgess K, Saragovi HU. Brahimi F, et al. Among authors: saragovi hu. Biochim Biophys Acta. 2010 Sep;1800(9):1018-26. doi: 10.1016/j.bbagen.2010.06.007. Epub 2010 Jun 19. Biochim Biophys Acta. 2010. PMID: 20600627 Free PMC article.

10

Chronic and acute models of retinal neurodegeneration TrkA activity are neuroprotective whereas p75NTR activity is neurotoxic through a paracrine mechanism.

Bai Y, Dergham P, Nedev H, Xu J, Galan A, Rivera JC, ZhiHua S, Mehta HM, Woo SB, Sarunic MV, Neet KE, Saragovi HU. Bai Y, et al. Among authors: saragovi hu. J Biol Chem. 2010 Dec 10;285(50):39392-400. doi: 10.1074/jbc.M110.147801. Epub 2010 Oct 13. J Biol Chem. 2010. PMID: 20943663 Free PMC article.

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