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Page 1
Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity.
Ji Y, Sun S, Shrestha N, Darragh LB, Shirakawa J, Xing Y, He Y, Carboneau BA, Kim H, An D, Ma M, Oberholzer J, Soleimanpour SA, Gannon M, Liu C, Naji A, Kulkarni RN, Wang Y, Kersten S, Qi L. Ji Y, et al. Among authors: darragh lb. Nat Immunol. 2019 Jun;20(6):677-686. doi: 10.1038/s41590-019-0396-z. Epub 2019 May 20. Nat Immunol. 2019. PMID: 31110312 Free PMC article.
Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC.
Abdelazeem KNM, Nguyen D, Corbo S, Darragh LB, Matsumoto MW, Court BV, Neupert B, Yu J, Olimpo NA, Osborne DG, Gadwa J, Ross RB, Nguyen A, Bhatia S, Kapoor M, Friedman RS, Jacobelli J, Saviola AJ, Knitz MW, Pasquale EB, Karam SD. Abdelazeem KNM, et al. Among authors: darragh lb. bioRxiv [Preprint]. 2024 Jul 23:2024.07.21.604518. doi: 10.1101/2024.07.21.604518. bioRxiv. 2024. Update in: Oncogene. 2024 Nov 3. doi: 10.1038/s41388-024-03208-9 PMID: 39091728 Free PMC article. Updated. Preprint.
Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer.
Mueller AC, Piper M, Goodspeed A, Bhuvane S, Williams JS, Bhatia S, Phan AV, Van Court B, Zolman KL, Peña B, Oweida AJ, Zakem S, Meguid C, Knitz MW, Darragh L, Bickett TE, Gadwa J, Mestroni L, Taylor MRG, Jordan KR, Dempsey P, Lucia MS, McCarter MD, Del Chiaro M, Messersmith WA, Schulick RD, Goodman KA, Gough MJ, Greene CS, Costello JC, Neto AG, Lagares D, Hansen KC, Van Bokhoven A, Karam SD. Mueller AC, et al. Cancer Res. 2021 Jun 15;81(12):3255-3269. doi: 10.1158/0008-5472.CAN-20-3892. Epub 2021 Feb 1. Cancer Res. 2021. PMID: 33526513 Free PMC article.
EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.
Bhatia S, Nguyen D, Darragh LB, Van Court B, Sharma J, Knitz MW, Piper M, Bukkapatnam S, Gadwa J, Bickett TE, Bhuvane S, Corbo S, Wu B, Lee Y, Fujita M, Joshi M, Heasley LE, Ferris RL, Rodriguez O, Albanese C, Kapoor M, Pasquale EB, Karam SD. Bhatia S, et al. Among authors: darragh lb. Nat Commun. 2022 Jun 20;13(1):3535. doi: 10.1038/s41467-022-31124-7. Nat Commun. 2022. PMID: 35725568 Free PMC article.
A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC.
Darragh LB, Knitz MM, Hu J, Clambey ET, Backus J, Dumit A, Samedi V, Bubak A, Greene C, Waxweiler T, Mehrotra S, Bhatia S, Gadwa J, Bickett T, Piper M, Fakhoury K, Liu A, Petit J, Bowles D, Thaker A, Atiyeh K, Goddard J, Hoyer R, Van Bokhoven A, Jordan K, Jimeno A, D'Alessandro A, Raben D, McDermott JD, Karam SD. Darragh LB, et al. Nat Cancer. 2022 Nov;3(11):1300-1317. doi: 10.1038/s43018-022-00450-6. Epub 2022 Nov 25. Nat Cancer. 2022. PMID: 36434392 Free PMC article. Clinical Trial.
Author Correction: A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC.
Darragh LB, Knitz MM, Hu J, Clambey ET, Backus J, Dumit A, Samedi V, Bubak A, Greene C, Waxweiler T, Mehrotra S, Bhatia S, Gadwa J, Bickett T, Piper M, Fakhoury K, Liu A, Petit J, Bowles D, Thaker A, Atiyeh K, Goddard J, Hoyer R, Van Bokhoven A, Jordan K, Jimeno A, D'Alessandro A, Raben D, McDermott JD, Karam SD. Darragh LB, et al. Nat Cancer. 2023 Jan;4(1):148. doi: 10.1038/s43018-022-00507-6. Nat Cancer. 2023. PMID: 36577897 Free PMC article. No abstract available.
Publisher Correction: A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC.
Darragh LB, Knitz MM, Hu J, Clambey ET, Backus J, Dumit A, Samedi V, Bubak A, Greene C, Waxweiler T, Mehrotra S, Bhatia S, Gadwa J, Bickett T, Piper M, Fakhoury K, Liu A, Petit J, Bowles D, Thaker A, Atiyeh K, Goddard J, Hoyer R, Van Bokhoven A, Jordan K, Jimeno A, D'Alessandro A, Raben D, McDermott JD, Karam SD. Darragh LB, et al. Nat Cancer. 2024 Jan;5(1):210. doi: 10.1038/s43018-024-00724-1. Nat Cancer. 2024. PMID: 38200246 Free PMC article. No abstract available.
IL7 in combination with radiotherapy stimulates a memory T-cell response to improve outcomes in HNSCC models.
Yu J, Gadwa J, Ross RB, Knitz M, Darragh LB, Abdelazeem KNM, Beynor J, Neupert B, Nguyen A, Nguyen D, Olimpo N, Corbo S, Van Court B, D'Alessandro A, Saviola A, Karam SD. Yu J, et al. Among authors: darragh lb. Cancer Immunol Immunother. 2024 Mar 30;73(5):90. doi: 10.1007/s00262-024-03664-y. Cancer Immunol Immunother. 2024. PMID: 38554147 Free PMC article.
The effects of ephrinB2 signaling on proliferation and invasion in glioblastoma multiforme.
Bhatia S, Bukkapatnam S, Van Court B, Phan A, Oweida A, Gadwa J, Mueller AC, Piper M, Darragh L, Nguyen D, Gilani A, Knitz M, Bickett T, Green A, Venkataraman S, Vibhakar R, Cittelly D, Karam SD. Bhatia S, et al. Mol Carcinog. 2020 Sep;59(9):1064-1075. doi: 10.1002/mc.23237. Epub 2020 Jun 22. Mol Carcinog. 2020. PMID: 32567728 Free PMC article.
31 results