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Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity.
Ji Y, Sun S, Shrestha N, Darragh LB, Shirakawa J, Xing Y, He Y, Carboneau BA, Kim H, An D, Ma M, Oberholzer J, Soleimanpour SA, Gannon M, Liu C, Naji A, Kulkarni RN, Wang Y, Kersten S, Qi L. Ji Y, et al. Among authors: oberholzer j. Nat Immunol. 2019 Jun;20(6):677-686. doi: 10.1038/s41590-019-0396-z. Epub 2019 May 20. Nat Immunol. 2019. PMID: 31110312 Free PMC article.
IG20/MADD plays a critical role in glucose-induced insulin secretion.
Li LC, Wang Y, Carr R, Haddad CS, Li Z, Qian L, Oberholzer J, Maker AV, Wang Q, Prabhakar BS. Li LC, et al. Among authors: oberholzer j. Diabetes. 2014 May;63(5):1612-23. doi: 10.2337/db13-0707. Epub 2013 Dec 30. Diabetes. 2014. PMID: 24379354 Free PMC article.
Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates.
Veiseh O, Doloff JC, Ma M, Vegas AJ, Tam HH, Bader AR, Li J, Langan E, Wyckoff J, Loo WS, Jhunjhunwala S, Chiu A, Siebert S, Tang K, Hollister-Lock J, Aresta-Dasilva S, Bochenek M, Mendoza-Elias J, Wang Y, Qi M, Lavin DM, Chen M, Dholakia N, Thakrar R, Lacík I, Weir GC, Oberholzer J, Greiner DL, Langer R, Anderson DG. Veiseh O, et al. Among authors: oberholzer j. Nat Mater. 2015 Jun;14(6):643-51. doi: 10.1038/nmat4290. Epub 2015 May 18. Nat Mater. 2015. PMID: 25985456 Free PMC article.
National Institutes of Health-Sponsored Clinical Islet Transplantation Consortium Phase 3 Trial: Manufacture of a Complex Cellular Product at Eight Processing Facilities.
Ricordi C, Goldstein JS, Balamurugan AN, Szot GL, Kin T, Liu C, Czarniecki CW, Barbaro B, Bridges ND, Cano J, Clarke WR, Eggerman TL, Hunsicker LG, Kaufman DB, Khan A, Lafontant DE, Linetsky E, Luo X, Markmann JF, Naji A, Korsgren O, Oberholzer J, Turgeon NA, Brandhorst D, Chen X, Friberg AS, Lei J, Wang LJ, Wilhelm JJ, Willits J, Zhang X, Hering BJ, Posselt AM, Stock PG, Shapiro AM, Chen X. Ricordi C, et al. Among authors: oberholzer j. Diabetes. 2016 Nov;65(11):3418-3428. doi: 10.2337/db16-0234. Epub 2016 Jul 27. Diabetes. 2016. PMID: 27465220 Free PMC article. Clinical Trial.
Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.
Chakravarthy H, Gu X, Enge M, Dai X, Wang Y, Damond N, Downie C, Liu K, Wang J, Xing Y, Chera S, Thorel F, Quake S, Oberholzer J, MacDonald PE, Herrera PL, Kim SK. Chakravarthy H, et al. Among authors: oberholzer j. Cell Metab. 2017 Mar 7;25(3):622-634. doi: 10.1016/j.cmet.2017.01.009. Epub 2017 Feb 16. Cell Metab. 2017. PMID: 28215845 Free PMC article.
336 results