Gao P - Search Results

1

Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression.

Lama L, Adura C, Xie W, Tomita D, Kamei T, Kuryavyi V, Gogakos T, Steinberg JI, Miller M, Ramos-Espiritu L, Asano Y, Hashizume S, Aida J, Imaeda T, Okamoto R, Jennings AJ, Michino M, Kuroita T, Stamford A, Gao P, Meinke P, Glickman JF, Patel DJ, Tuschl T. Lama L, et al. Among authors: gao p. Nat Commun. 2019 May 21;10(1):2261. doi: 10.1038/s41467-019-08620-4. Nat Commun. 2019. PMID: 31113940 Free PMC article.

2

SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action.

Oh YS, Gao P, Lee KW, Ceglia I, Seo JS, Zhang X, Ahn JH, Chait BT, Patel DJ, Kim Y, Greengard P. Oh YS, et al. Among authors: gao p. Cell. 2013 Feb 14;152(4):831-43. doi: 10.1016/j.cell.2013.01.014. Cell. 2013. PMID: 23415230 Free PMC article.

3

Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.

Gao P, Ascano M, Wu Y, Barchet W, Gaffney BL, Zillinger T, Serganov AA, Liu Y, Jones RA, Hartmann G, Tuschl T, Patel DJ. Gao P, et al. Cell. 2013 May 23;153(5):1094-107. doi: 10.1016/j.cell.2013.04.046. Epub 2013 May 3. Cell. 2013. PMID: 23647843 Free PMC article.

4

Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.

Gao P, Ascano M, Zillinger T, Wang W, Dai P, Serganov AA, Gaffney BL, Shuman S, Jones RA, Deng L, Hartmann G, Barchet W, Tuschl T, Patel DJ. Gao P, et al. Cell. 2013 Aug 15;154(4):748-62. doi: 10.1016/j.cell.2013.07.023. Epub 2013 Aug 1. Cell. 2013. PMID: 23910378 Free PMC article.

5

Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA.

Gao P, Zillinger T, Wang W, Ascano M, Dai P, Hartmann G, Tuschl T, Deng L, Barchet W, Patel DJ. Gao P, et al. Cell Rep. 2014 Sep 25;8(6):1668-1676. doi: 10.1016/j.celrep.2014.08.010. Epub 2014 Sep 4. Cell Rep. 2014. PMID: 25199835 Free PMC article.

6

V-cGAPs: attenuators of 3'3'-cGAMP signaling.

Gao P, Patel DJ. Gao P, et al. Cell Res. 2015 May;25(5):529-30. doi: 10.1038/cr.2015.48. Epub 2015 Apr 24. Cell Res. 2015. PMID: 25906992 Free PMC article.

7

Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage.

Ren A, Vušurović N, Gebetsberger J, Gao P, Juen M, Kreutz C, Micura R, Patel DJ. Ren A, et al. Among authors: gao p. Nat Chem Biol. 2016 Sep;12(9):702-8. doi: 10.1038/nchembio.2125. Epub 2016 Jul 11. Nat Chem Biol. 2016. PMID: 27398999 Free PMC article.

8

Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition.

Gao P, Yang H, Rajashankar KR, Huang Z, Patel DJ. Gao P, et al. Cell Res. 2016 Aug;26(8):901-13. doi: 10.1038/cr.2016.88. Epub 2016 Jul 22. Cell Res. 2016. PMID: 27444870 Free PMC article.

9

DNA sensor cGAS-mediated immune recognition.

Xia P, Wang S, Gao P, Gao G, Fan Z. Xia P, et al. Among authors: gao g, gao p. Protein Cell. 2016 Nov;7(11):777-791. doi: 10.1007/s13238-016-0320-3. Epub 2016 Sep 30. Protein Cell. 2016. PMID: 27696330 Free PMC article. Review.

10

PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease.

Yang H, Gao P, Rajashankar KR, Patel DJ. Yang H, et al. Among authors: gao p. Cell. 2016 Dec 15;167(7):1814-1828.e12. doi: 10.1016/j.cell.2016.11.053. Cell. 2016. PMID: 27984729 Free PMC article.

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