Ruvolo VR - Search Results

1

Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models.

Han L, Zhang Q, Dail M, Shi C, Cavazos A, Ruvolo VR, Zhao Y, Kim E, Rahmani M, Mak DH, Jin SS, Chen J, Phillips DC, Koller PB, Jacamo R, Burks JK, DiNardo C, Daver N, Jabbour E, Wang J, Kantarjian HM, Andreeff M, Grant S, Leverson JD, Sampath D, Konopleva M. Han L, et al. Among authors: ruvolo vr. Haematologica. 2020 Mar;105(3):697-707. doi: 10.3324/haematol.2018.205534. Epub 2019 May 23. Haematologica. 2020. PMID: 31123034 Free PMC article.

2

Isolation and characterization of a hypervariable region [D4S163] on chromosome 4.

Neuweiler J, Ruvolo V, Baum H, Grzeschik KH, Balazs I. Neuweiler J, et al. Nucleic Acids Res. 1990 Feb 11;18(3):691. doi: 10.1093/nar/18.3.691. Nucleic Acids Res. 1990. PMID: 1968629 Free PMC article.

3

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy.

Kojima K, Konopleva M, Samudio IJ, Shikami M, Cabreira-Hansen M, McQueen T, Ruvolo V, Tsao T, Zeng Z, Vassilev LT, Andreeff M. Kojima K, et al. Blood. 2005 Nov 1;106(9):3150-9. doi: 10.1182/blood-2005-02-0553. Epub 2005 Jul 12. Blood. 2005. PMID: 16014563 Free PMC article.

4

PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.

Tabe Y, Konopleva M, Kondo Y, Contractor R, Jin L, Ruvolo V, Tsutsumi-Ishii Y, Miyake K, Miyake N, Ohsaka A, Nagaoka I, Issa JP, Andreeff M. Tabe Y, et al. Ann Hematol. 2006 Oct;85(10):689-704. doi: 10.1007/s00277-006-0148-7. Epub 2006 Jul 11. Ann Hematol. 2006. PMID: 16832676

5

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.

Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S, Deng X, Zhai D, Shi YX, Sneed T, Verhaegen M, Soengas M, Ruvolo VR, McQueen T, Schober WD, Watt JC, Jiffar T, Ling X, Marini FC, Harris D, Dietrich M, Estrov Z, McCubrey J, May WS, Reed JC, Andreeff M. Konopleva M, et al. Among authors: ruvolo pp, ruvolo vr. Cancer Cell. 2006 Nov;10(5):375-88. doi: 10.1016/j.ccr.2006.10.006. Cancer Cell. 2006. PMID: 17097560 Free article.

6

Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells.

Kojima K, Konopleva M, Samudio IJ, Ruvolo V, Andreeff M. Kojima K, et al. Cancer Res. 2007 Apr 1;67(7):3210-9. doi: 10.1158/0008-5472.CAN-06-2712. Cancer Res. 2007. PMID: 17409429

7

The novel triterpenoid C-28 methyl ester of 2-cyano-3, 12-dioxoolen-1, 9-dien-28-oic acid inhibits metastatic murine breast tumor growth through inactivation of STAT3 signaling.

Ling X, Konopleva M, Zeng Z, Ruvolo V, Stephens LC, Schober W, McQueen T, Dietrich M, Madden TL, Andreeff M. Ling X, et al. Cancer Res. 2007 May 1;67(9):4210-8. doi: 10.1158/0008-5472.CAN-06-3629. Cancer Res. 2007. PMID: 17483332

8

Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia.

Mullican SE, Zhang S, Konopleva M, Ruvolo V, Andreeff M, Milbrandt J, Conneely OM. Mullican SE, et al. Nat Med. 2007 Jun;13(6):730-5. doi: 10.1038/nm1579. Epub 2007 May 21. Nat Med. 2007. PMID: 17515897

9

Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway.

Zhang W, Konopleva M, Ruvolo VR, McQueen T, Evans RL, Bornmann WG, McCubrey J, Cortes J, Andreeff M. Zhang W, et al. Among authors: ruvolo vr. Leukemia. 2008 Apr;22(4):808-18. doi: 10.1038/sj.leu.2405098. Epub 2008 Jan 17. Leukemia. 2008. PMID: 18200035

10

The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML.

Kojima K, Shimanuki M, Shikami M, Samudio IJ, Ruvolo V, Corn P, Hanaoka N, Konopleva M, Andreeff M, Nakakuma H. Kojima K, et al. Leukemia. 2008 Sep;22(9):1728-36. doi: 10.1038/leu.2008.158. Epub 2008 Jun 12. Leukemia. 2008. PMID: 18548093

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