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Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis.
Nielsen R, Pedersen TA, Hagenbeek D, Moulos P, Siersbaek R, Megens E, Denissov S, Børgesen M, Francoijs KJ, Mandrup S, Stunnenberg HG. Nielsen R, et al. Among authors: mandrup s. Genes Dev. 2008 Nov 1;22(21):2953-67. doi: 10.1101/gad.501108. Genes Dev. 2008. PMID: 18981474 Free PMC article.
TLE3 is a dual-function transcriptional coregulator of adipogenesis.
Villanueva CJ, Waki H, Godio C, Nielsen R, Chou WL, Vargas L, Wroblewski K, Schmedt C, Chao LC, Boyadjian R, Mandrup S, Hevener A, Saez E, Tontonoz P. Villanueva CJ, et al. Among authors: mandrup s. Cell Metab. 2011 Apr 6;13(4):413-427. doi: 10.1016/j.cmet.2011.02.014. Cell Metab. 2011. PMID: 21459326 Free PMC article.
Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding correlated with gene expression.
Siersbæk MS, Loft A, Aagaard MM, Nielsen R, Schmidt SF, Petrovic N, Nedergaard J, Mandrup S. Siersbæk MS, et al. Among authors: mandrup s. Mol Cell Biol. 2012 Sep;32(17):3452-63. doi: 10.1128/MCB.00526-12. Epub 2012 Jun 25. Mol Cell Biol. 2012. PMID: 22733994 Free PMC article.
Transcription factor cooperativity in early adipogenic hotspots and super-enhancers.
Siersbæk R, Rabiee A, Nielsen R, Sidoli S, Traynor S, Loft A, Poulsen LC, Rogowska-Wrzesinska A, Jensen ON, Mandrup S. Siersbæk R, et al. Among authors: mandrup s. Cell Rep. 2014 Jun 12;7(5):1443-1455. doi: 10.1016/j.celrep.2014.04.042. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857652 Free article.
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers.
Loft A, Forss I, Siersbæk MS, Schmidt SF, Larsen AS, Madsen JG, Pisani DF, Nielsen R, Aagaard MM, Mathison A, Neville MJ, Urrutia R, Karpe F, Amri EZ, Mandrup S. Loft A, et al. Among authors: mandrup s. Genes Dev. 2015 Jan 1;29(1):7-22. doi: 10.1101/gad.250829.114. Epub 2014 Dec 12. Genes Dev. 2015. PMID: 25504365 Free PMC article.
158 results