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Page 1
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.
Puleston DJ, Buck MD, Klein Geltink RI, Kyle RL, Caputa G, O'Sullivan D, Cameron AM, Castoldi A, Musa Y, Kabat AM, Zhang Y, Flachsmann LJ, Field CS, Patterson AE, Scherer S, Alfei F, Baixauli F, Austin SK, Kelly B, Matsushita M, Curtis JD, Grzes KM, Villa M, Corrado M, Sanin DE, Qiu J, Pällman N, Paz K, Maccari ME, Blazar BR, Mittler G, Buescher JM, Zehn D, Rospert S, Pearce EJ, Balabanov S, Pearce EL. Puleston DJ, et al. Among authors: flachsmann lj. Cell Metab. 2019 Aug 6;30(2):352-363.e8. doi: 10.1016/j.cmet.2019.05.003. Epub 2019 May 23. Cell Metab. 2019. PMID: 31130465 Free PMC article.
Macrophage metabolism: a wound-healing perspective.
Caputa G, Flachsmann LJ, Cameron AM. Caputa G, et al. Among authors: flachsmann lj. Immunol Cell Biol. 2019 Mar;97(3):268-278. doi: 10.1111/imcb.12237. Epub 2019 Feb 21. Immunol Cell Biol. 2019. PMID: 30779212 Review.
Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity.
Corrado M, Edwards-Hicks J, Villa M, Flachsmann LJ, Sanin DE, Jacobs M, Baixauli F, Stanczak M, Anderson E, Azuma M, Quintana A, Curtis JD, Clapes T, Grzes KM, Kabat AM, Kyle R, Patterson AE, Geltink RK, Amulic B, Steward CG, Strathdee D, Trompouki E, O'Sullivan D, Pearce EJ, Pearce EL. Corrado M, et al. Among authors: flachsmann lj. Cell Metab. 2020 Dec 1;32(6):981-995.e7. doi: 10.1016/j.cmet.2020.11.003. Cell Metab. 2020. PMID: 33264603 Free PMC article.
Polyamine metabolism is a central determinant of helper T cell lineage fidelity.
Puleston DJ, Baixauli F, Sanin DE, Edwards-Hicks J, Villa M, Kabat AM, Kamiński MM, Stanckzak M, Weiss HJ, Grzes KM, Piletic K, Field CS, Corrado M, Haessler F, Wang C, Musa Y, Schimmelpfennig L, Flachsmann L, Mittler G, Yosef N, Kuchroo VK, Buescher JM, Balabanov S, Pearce EJ, Green DR, Pearce EL. Puleston DJ, et al. Cell. 2021 Aug 5;184(16):4186-4202.e20. doi: 10.1016/j.cell.2021.06.007. Epub 2021 Jul 2. Cell. 2021. PMID: 34216540 Free PMC article.
Intracellular infection and immune system cues rewire adipocytes to acquire immune function.
Caputa G, Matsushita M, Sanin DE, Kabat AM, Edwards-Hicks J, Grzes KM, Pohlmeyer R, Stanczak MA, Castoldi A, Cupovic J, Forde AJ, Apostolova P, Seidl M, van Teijlingen Bakker N, Villa M, Baixauli F, Quintana A, Hackl A, Flachsmann L, Hässler F, Curtis JD, Patterson AE, Henneke P, Pearce EL, Pearce EJ. Caputa G, et al. Cell Metab. 2022 May 3;34(5):747-760.e6. doi: 10.1016/j.cmet.2022.04.008. Cell Metab. 2022. PMID: 35508110 Free article.
An LKB1-mitochondria axis controls TH17 effector function.
Baixauli F, Piletic K, Puleston DJ, Villa M, Field CS, Flachsmann LJ, Quintana A, Rana N, Edwards-Hicks J, Matsushita M, Stanczak MA, Grzes KM, Kabat AM, Fabri M, Caputa G, Kelly B, Corrado M, Musa Y, Duda KJ, Mittler G, O'Sullivan D, Sesaki H, Jenuwein T, Buescher JM, Pearce EJ, Sanin DE, Pearce EL. Baixauli F, et al. Among authors: flachsmann lj. Nature. 2022 Oct;610(7932):555-561. doi: 10.1038/s41586-022-05264-1. Epub 2022 Sep 28. Nature. 2022. PMID: 36171294 Free PMC article.
Sulfur sequestration promotes multicellularity during nutrient limitation.
Kelly B, Carrizo GE, Edwards-Hicks J, Sanin DE, Stanczak MA, Priesnitz C, Flachsmann LJ, Curtis JD, Mittler G, Musa Y, Becker T, Buescher JM, Pearce EL. Kelly B, et al. Among authors: flachsmann lj. Nature. 2021 Mar;591(7850):471-476. doi: 10.1038/s41586-021-03270-3. Epub 2021 Feb 24. Nature. 2021. PMID: 33627869 Free PMC article.
Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function.
Hartl FA, Beck-Garcìa E, Woessner NM, Flachsmann LJ, Cárdenas RMV, Brandl SM, Taromi S, Fiala GJ, Morath A, Mishra P, Yousefi OS, Zimmermann J, Hoefflin N, Köhn M, Wöhrl BM, Zeiser R, Schweimer K, Günther S, Schamel WW, Minguet S. Hartl FA, et al. Among authors: flachsmann lj. Nat Immunol. 2020 Aug;21(8):902-913. doi: 10.1038/s41590-020-0732-3. Epub 2020 Jul 20. Nat Immunol. 2020. PMID: 32690949
Author Correction: Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function.
Hartl FA, Beck-Garcìa E, Woessner NM, Flachsmann LJ, Cárdenas RMV, Brandl SM, Taromi S, Fiala GJ, Morath A, Mishra P, Yousefi OS, Zimmermann J, Hoefflin N, Köhn M, Wöhrl BM, Zeiser R, Schweimer K, Günther S, Schamel WW, Minguet S. Hartl FA, et al. Among authors: flachsmann lj. Nat Immunol. 2021 Jan;22(1):100-101. doi: 10.1038/s41590-020-00843-8. Nat Immunol. 2021. PMID: 33214721 No abstract available.