Chen X - Search Results

1

A substrate tagging and two-step enzymatic reaction strategy for large-scale synthesis of 2,7-anhydro-sialic acid.

Li W, Ghosh T, Bai Y, Santra A, Xiao A, Chen X. Li W, et al. Among authors: chen x. Carbohydr Res. 2019 Jun 1;479:41-47. doi: 10.1016/j.carres.2019.05.002. Epub 2019 May 16. Carbohydr Res. 2019. PMID: 31132641 Free PMC article.

2

Chemoenzymatic synthesis of CMP-sialic acid derivatives by a one-pot two-enzyme system: comparison of substrate flexibility of three microbial CMP-sialic acid synthetases.

Yu H, Yu H, Karpel R, Chen X. Yu H, et al. Among authors: chen x. Bioorg Med Chem. 2004 Dec 15;12(24):6427-35. doi: 10.1016/j.bmc.2004.09.030. Bioorg Med Chem. 2004. PMID: 15556760

3

Chemical preparation of sialyl Lewis x using an enzymatically synthesized sialoside building block.

Cao H, Huang S, Cheng J, Li Y, Muthana S, Son B, Chen X. Cao H, et al. Among authors: chen x. Carbohydr Res. 2008 Nov 24;343(17):2863-9. doi: 10.1016/j.carres.2008.06.020. Epub 2008 Jul 4. Carbohydr Res. 2008. PMID: 18639240 Free PMC article.

4

Combinatorial chemoenzymatic synthesis and high-throughput screening of sialosides.

Chokhawala HA, Huang S, Lau K, Yu H, Cheng J, Thon V, Hurtado-Ziola N, Guerrero JA, Varki A, Chen X. Chokhawala HA, et al. Among authors: chen x. ACS Chem Biol. 2008 Sep 19;3(9):567-76. doi: 10.1021/cb800127n. Epub 2008 Aug 27. ACS Chem Biol. 2008. PMID: 18729452 Free PMC article.

5

Parallel chemoenzymatic synthesis of sialosides containing a C5-diversified sialic acid.

Cao H, Muthana S, Li Y, Cheng J, Chen X. Cao H, et al. Among authors: chen x. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5869-71. doi: 10.1016/j.bmcl.2009.08.078. Epub 2009 Aug 26. Bioorg Med Chem Lett. 2009. PMID: 19740656 Free PMC article.

6

Trans-sialidase activity of Photobacterium damsela alpha2,6-sialyltransferase and its application in the synthesis of sialosides.

Cheng J, Huang S, Yu H, Li Y, Lau K, Chen X. Cheng J, et al. Among authors: chen x. Glycobiology. 2010 Feb;20(2):260-8. doi: 10.1093/glycob/cwp172. Epub 2009 Oct 30. Glycobiology. 2010. PMID: 19880425 Free PMC article.

7

Chemoenzymatic synthesis of GD3 oligosaccharides and other disialyl glycans containing natural and non-natural sialic acids.

Yu H, Cheng J, Ding L, Khedri Z, Chen Y, Chin S, Lau K, Tiwari VK, Chen X. Yu H, et al. Among authors: chen x, chen y. J Am Chem Soc. 2009 Dec 30;131(51):18467-77. doi: 10.1021/ja907750r. J Am Chem Soc. 2009. PMID: 19947630 Free PMC article.

8

Advances in the biology and chemistry of sialic acids.

Chen X, Varki A. Chen X, et al. ACS Chem Biol. 2010 Feb 19;5(2):163-76. doi: 10.1021/cb900266r. ACS Chem Biol. 2010. PMID: 20020717 Free PMC article. Review.

9

Sequential two-step multienzyme synthesis of tumor-associated sialyl T-antigens and derivatives.

Lau K, Yu H, Thon V, Khedri Z, Leon ME, Tran BK, Chen X. Lau K, et al. Among authors: chen x. Org Biomol Chem. 2011 Apr 21;9(8):2784-9. doi: 10.1039/c0ob01269f. Epub 2011 Mar 1. Org Biomol Chem. 2011. PMID: 21359399 Free PMC article.

10

Sialic acid metabolism and sialyltransferases: natural functions and applications.

Li Y, Chen X. Li Y, et al. Among authors: chen x. Appl Microbiol Biotechnol. 2012 May;94(4):887-905. doi: 10.1007/s00253-012-4040-1. Epub 2012 Apr 13. Appl Microbiol Biotechnol. 2012. PMID: 22526796 Free PMC article. Review.

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