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Apurinic/apyrimidinic endonuclease 1/reduction-oxidation effector factor-1 (APE1) regulates the expression of NLR family pyrin domain containing 3 (NLRP3) inflammasome through modulating transcription factor NF-κB and promoting the secretion of inflammatory mediators in macrophages.
Tang Z, Wang Y, Wan Y, Xie Y, Li S, Tao D, Wang C, Wu YZ, Sui JD. Tang Z, et al. Among authors: wang y, wang c. Ann Transl Med. 2021 Jan;9(2):145. doi: 10.21037/atm-20-7752. Ann Transl Med. 2021. PMID: 33569447 Free PMC article.
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