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LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex.
Cirnaru MD, Marte A, Belluzzi E, Russo I, Gabrielli M, Longo F, Arcuri L, Murru L, Bubacco L, Matteoli M, Fedele E, Sala C, Passafaro M, Morari M, Greggio E, Onofri F, Piccoli G. Cirnaru MD, et al. Among authors: fedele e. Front Mol Neurosci. 2014 May 27;7:49. doi: 10.3389/fnmol.2014.00049. eCollection 2014. Front Mol Neurosci. 2014. PMID: 24904275 Free PMC article.
Exocytosis regulates trafficking of GABA and glycine heterotransporters in spinal cord glutamatergic synapses: a mechanism for the excessive heterotransporter-induced release of glutamate in experimental amyotrophic lateral sclerosis.
Milanese M, Bonifacino T, Fedele E, Rebosio C, Cattaneo L, Benfenati F, Usai C, Bonanno G. Milanese M, et al. Among authors: fedele e. Neurobiol Dis. 2015 Feb;74:314-24. doi: 10.1016/j.nbd.2014.12.004. Epub 2014 Dec 10. Neurobiol Dis. 2015. PMID: 25497732
156 results