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pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages.
Kaps L, Huppertsberg A, Choteschovsky N, Klefenz A, Durak F, Schrörs B, Diken M, Eichler E, Rosigkeit S, Schmitt S, Leps C, Schulze A, Foerster F, Bockamp E, De Geest BG, Koynov K, Räder HJ, Tenzer S, Marini F, Schuppan D, Nuhn L. Kaps L, et al. Among authors: choteschovsky n. Proc Natl Acad Sci U S A. 2022 Mar 22;119(12):e2122310119. doi: 10.1073/pnas.2122310119. Epub 2022 Mar 15. Proc Natl Acad Sci U S A. 2022. PMID: 35290110 Free PMC article.
Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators.
Huppertsberg A, Kaps L, Zhong Z, Schmitt S, Stickdorn J, Deswarte K, Combes F, Czysch C, De Vrieze J, Kasmi S, Choteschovsky N, Klefenz A, Medina-Montano C, Winterwerber P, Chen C, Bros M, Lienenklaus S, Sanders NN, Koynov K, Schuppan D, Lambrecht BN, David SA, De Geest BG, Nuhn L. Huppertsberg A, et al. Among authors: choteschovsky n. J Am Chem Soc. 2021 Jul 7;143(26):9872-9883. doi: 10.1021/jacs.1c03772. Epub 2021 Jun 24. J Am Chem Soc. 2021. PMID: 34166595 Free PMC article.