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Page 1
Intraductal Papillary Mucinous Neoplasms Arise From Multiple Independent Clones, Each With Distinct Mutations.
Fischer CG, Beleva Guthrie V, Braxton AM, Zheng L, Wang P, Song Q, Griffin JF, Chianchiano PE, Hosoda W, Niknafs N, Springer S, Dal Molin M, Masica D, Scharpf RB, Thompson ED, He J, Wolfgang CL, Hruban RH, Roberts NJ, Lennon AM, Jiao Y, Karchin R, Wood LD. Fischer CG, et al. Among authors: braxton am. Gastroenterology. 2019 Oct;157(4):1123-1137.e22. doi: 10.1053/j.gastro.2019.06.001. Epub 2019 Jun 5. Gastroenterology. 2019. PMID: 31175866 Free PMC article.
Three-dimensional visualization of cleared human pancreas cancer reveals that sustained epithelial-to-mesenchymal transition is not required for venous invasion.
Hong SM, Jung D, Kiemen A, Gaida MM, Yoshizawa T, Braxton AM, Noë M, Lionheart G, Oshima K, Thompson ED, Burkhart R, Wu PH, Wirtz D, Hruban RH, Wood LD. Hong SM, et al. Among authors: braxton am. Mod Pathol. 2020 Apr;33(4):639-647. doi: 10.1038/s41379-019-0409-3. Epub 2019 Nov 7. Mod Pathol. 2020. PMID: 31700162 Free PMC article.
Multiregion whole-exome sequencing of intraductal papillary mucinous neoplasms reveals frequent somatic KLF4 mutations predominantly in low-grade regions.
Fujikura K, Hosoda W, Felsenstein M, Song Q, Reiter JG, Zheng L, Beleva Guthrie V, Rincon N, Dal Molin M, Dudley J, Cohen JD, Wang P, Fischer CG, Braxton AM, Noë M, Jongepier M, Fernández-Del Castillo C, Mino-Kenudson M, Schmidt CM, Yip-Schneider MT, Lawlor RT, Salvia R, Roberts NJ, Thompson ED, Karchin R, Lennon AM, Jiao Y, Wood LD. Fujikura K, et al. Among authors: braxton am. Gut. 2021 May;70(5):928-939. doi: 10.1136/gutjnl-2020-321217. Epub 2020 Oct 7. Gut. 2021. PMID: 33028669 Free PMC article.
CODA: quantitative 3D reconstruction of large tissues at cellular resolution.
Kiemen AL, Braxton AM, Grahn MP, Han KS, Babu JM, Reichel R, Jiang AC, Kim B, Hsu J, Amoa F, Reddy S, Hong SM, Cornish TC, Thompson ED, Huang P, Wood LD, Hruban RH, Wirtz D, Wu PH. Kiemen AL, et al. Among authors: braxton am. Nat Methods. 2022 Nov;19(11):1490-1499. doi: 10.1038/s41592-022-01650-9. Epub 2022 Oct 24. Nat Methods. 2022. PMID: 36280719 Free PMC article.
Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer.
Kiemen AL, Choi Y, Braxton AM, Almagro Pérez C, Graham S, Grahn MP, Nanda N, Roberts N, Wood L, Wu P, Hruban RH, Wirtz D. Kiemen AL, et al. Among authors: braxton am. Histopathology. 2023 Feb;82(3):504-506. doi: 10.1111/his.14839. Epub 2022 Nov 21. Histopathology. 2023. PMID: 36371607 Free PMC article.
Three-dimensional genomic mapping of human pancreatic tissue reveals striking multifocality and genetic heterogeneity in precancerous lesions.
Braxton AM, Kiemen AL, Grahn MP, Forjaz A, Babu JM, Zheng L, Jiang L, Cheng H, Song Q, Reichel R, Graham S, Damanakis AI, Fischer CG, Mou S, Metz C, Granger J, Liu XD, Bachmann N, Almagro-Pérez C, Jiang AC, Yoo J, Kim B, Du S, Foster E, Hsu JY, Rivera PA, Chu LC, Liu F, Niknafs N, Fishman EK, Yuille A, Roberts NJ, Thompson ED, Scharpf RB, Cornish TC, Jiao Y, Karchin R, Hruban RH, Wu PH, Wirtz D, Wood LD. Braxton AM, et al. bioRxiv [Preprint]. 2023 Jan 28:2023.01.27.525553. doi: 10.1101/2023.01.27.525553. bioRxiv. 2023. PMID: 36747709 Free PMC article. Preprint.
3D genomic mapping reveals multifocality of human pancreatic precancers.
Braxton AM, Kiemen AL, Grahn MP, Forjaz A, Parksong J, Mahesh Babu J, Lai J, Zheng L, Niknafs N, Jiang L, Cheng H, Song Q, Reichel R, Graham S, Damanakis AI, Fischer CG, Mou S, Metz C, Granger J, Liu XD, Bachmann N, Zhu Y, Liu Y, Almagro-Pérez C, Jiang AC, Yoo J, Kim B, Du S, Foster E, Hsu JY, Rivera PA, Chu LC, Liu F, Fishman EK, Yuille A, Roberts NJ, Thompson ED, Scharpf RB, Cornish TC, Jiao Y, Karchin R, Hruban RH, Wu PH, Wirtz D, Wood LD. Braxton AM, et al. Nature. 2024 May;629(8012):679-687. doi: 10.1038/s41586-024-07359-3. Epub 2024 May 1. Nature. 2024. PMID: 38693266
PanIN or IPMN? Redefining Lesion Size in 3 Dimensions.
Kiemen AL, Dequiedt L, Shen Y, Zhu Y, Matos-Romero V, Forjaz A, Campbell K, Dhana W, Cornish T, Braxton AM, Wu PH, Fishman EK, Wood LD, Wirtz D, Hruban RH. Kiemen AL, et al. Among authors: braxton am. Am J Surg Pathol. 2024 Jul 1;48(7):839-845. doi: 10.1097/PAS.0000000000002245. Epub 2024 May 20. Am J Surg Pathol. 2024. PMID: 38764379
26 results