Prior AM - Search Results

1

Small-Molecule Inhibition of the C. difficile FAS-II Enzyme, FabK, Results in Selective Activity.

Jones JA, Prior AM, Marreddy RKR, Wahrmund RD, Hurdle JG, Sun D, Hevener KE. Jones JA, et al. Among authors: prior am. ACS Chem Biol. 2019 Jul 19;14(7):1528-1535. doi: 10.1021/acschembio.9b00293. Epub 2019 Jun 26. ACS Chem Biol. 2019. PMID: 31184849 Free PMC article.

2

The Fatty Acid Synthesis Protein Enoyl-ACP Reductase II (FabK) is a Target for Narrow-Spectrum Antibacterials for Clostridium difficile Infection.

Marreddy RKR, Wu X, Sapkota M, Prior AM, Jones JA, Sun D, Hevener KE, Hurdle JG. Marreddy RKR, et al. Among authors: prior am. ACS Infect Dis. 2019 Feb 8;5(2):208-217. doi: 10.1021/acsinfecdis.8b00205. Epub 2018 Dec 13. ACS Infect Dis. 2019. PMID: 30501172 Free PMC article.

3

Pharmacophore Modeling, Synthesis, and Antibacterial Evaluation of Chalcones and Derivatives.

Zhang M, Prior AM, Maddox MM, Shen WJ, Hevener KE, Bruhn DF, Lee RB, Singh AP, Reinicke J, Simmons CJ, Hurdle JG, Lee RE, Sun D. Zhang M, et al. Among authors: prior am. ACS Omega. 2018 Dec 31;3(12):18343-18360. doi: 10.1021/acsomega.8b03174. Epub 2018 Dec 26. ACS Omega. 2018. PMID: 30613820 Free PMC article.

4

Solid-Phase Synthesis of Wollamide Cyclohexapeptide Analogs.

Prior AM, Sun D. Prior AM, et al. Methods Mol Biol. 2020;2103:175-187. doi: 10.1007/978-1-0716-0227-0_11. Methods Mol Biol. 2020. PMID: 31879925

5

Total synthesis of diazaquinomycins H and J using double Knorr cyclization in the presence of triisopropylsilane.

Prior AM, Sun D. Prior AM, et al. RSC Adv. 2019 Jan 14;9(4):1759-1771. doi: 10.1039/c8ra09792e. eCollection 2019 Jan 14. RSC Adv. 2019. PMID: 35516148 Free PMC article.

6

Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1.

Prior AM, Yu X, Park EJ, Kondratyuk TP, Lin Y, Pezzuto JM, Sun D. Prior AM, et al. Bioorg Med Chem Lett. 2017 Dec 15;27(24):5393-5399. doi: 10.1016/j.bmcl.2017.11.010. Epub 2017 Nov 6. Bioorg Med Chem Lett. 2017. PMID: 29153737 Free PMC article.

7

Recent Reports of Solid-Phase Cyclohexapeptide Synthesis and Applications.

Prior AM, Hori T, Fishman A, Sun D. Prior AM, et al. Molecules. 2018 Jun 18;23(6):1475. doi: 10.3390/molecules23061475. Molecules. 2018. PMID: 29912160 Free PMC article. Review.

8

Inhibition of long chain fatty acyl-CoA synthetase (ACSL) and ischemia reperfusion injury.

Prior AM, Zhang M, Blakeman N, Datta P, Pham H, Chen Q, Young LH, Weis MT, Hua DH. Prior AM, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1057-61. doi: 10.1016/j.bmcl.2014.01.016. Epub 2014 Jan 13. Bioorg Med Chem Lett. 2014. PMID: 24480468 Free PMC article.

9

Design, synthesis, and bioevaluation of viral 3C and 3C-like protease inhibitors.

Prior AM, Kim Y, Weerasekara S, Moroze M, Alliston KR, Uy RA, Groutas WC, Chang KO, Hua DH. Prior AM, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6317-20. doi: 10.1016/j.bmcl.2013.09.070. Epub 2013 Sep 30. Bioorg Med Chem Lett. 2013. PMID: 24125888 Free PMC article.

10

Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus.

Mandadapu SR, Weerawarna PM, Prior AM, Uy RA, Aravapalli S, Alliston KR, Lushington GH, Kim Y, Hua DH, Chang KO, Groutas WC. Mandadapu SR, et al. Among authors: prior am. Bioorg Med Chem Lett. 2013 Jul 1;23(13):3709-12. doi: 10.1016/j.bmcl.2013.05.021. Epub 2013 May 16. Bioorg Med Chem Lett. 2013. PMID: 23727045 Free PMC article.

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