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O-GlcNAcylation of Histone Deacetylase 4 Protects the Diabetic Heart From Failure.
Kronlage M, Dewenter M, Grosso J, Fleming T, Oehl U, Lehmann LH, Falcão-Pires I, Leite-Moreira AF, Volk N, Gröne HJ, Müller OJ, Sickmann A, Katus HA, Backs J. Kronlage M, et al. Among authors: lehmann lh. Circulation. 2019 Aug 13;140(7):580-594. doi: 10.1161/CIRCULATIONAHA.117.031942. Epub 2019 Jun 14. Circulation. 2019. PMID: 31195810
The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload.
Backs J, Backs T, Neef S, Kreusser MM, Lehmann LH, Patrick DM, Grueter CE, Qi X, Richardson JA, Hill JA, Katus HA, Bassel-Duby R, Maier LS, Olson EN. Backs J, et al. Among authors: lehmann lh. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2342-7. doi: 10.1073/pnas.0813013106. Epub 2009 Jan 28. Proc Natl Acad Sci U S A. 2009. PMID: 19179290 Free PMC article.
Selective repression of MEF2 activity by PKA-dependent proteolysis of HDAC4.
Backs J, Worst BC, Lehmann LH, Patrick DM, Jebessa Z, Kreusser MM, Sun Q, Chen L, Heft C, Katus HA, Olson EN. Backs J, et al. Among authors: lehmann lh. J Cell Biol. 2011 Oct 31;195(3):403-15. doi: 10.1083/jcb.201105063. J Cell Biol. 2011. PMID: 22042619 Free PMC article.
HDAC4 controls histone methylation in response to elevated cardiac load.
Hohl M, Wagner M, Reil JC, Müller SA, Tauchnitz M, Zimmer AM, Lehmann LH, Thiel G, Böhm M, Backs J, Maack C. Hohl M, et al. Among authors: lehmann lh. J Clin Invest. 2013 Mar;123(3):1359-70. doi: 10.1172/JCI61084. Epub 2013 Feb 22. J Clin Invest. 2013. PMID: 23434587 Free PMC article.
Histone deacetylase signaling in cardioprotection.
Lehmann LH, Worst BC, Stanmore DA, Backs J. Lehmann LH, et al. Cell Mol Life Sci. 2014 May;71(9):1673-90. doi: 10.1007/s00018-013-1516-9. Epub 2013 Dec 6. Cell Mol Life Sci. 2014. PMID: 24310814 Free PMC article. Review.
87 results