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Page 1
Gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy.
Göös H, Fogarty CL, Sahu B, Plagnol V, Rajamäki K, Nurmi K, Liu X, Einarsdottir E, Jouppila A, Pettersson T, Vihinen H, Krjutskov K, Saavalainen P, Järvinen A, Muurinen M, Greco D, Scala G, Curtis J, Nordström D, Flaumenhaft R, Vaarala O, Kovanen PE, Keskitalo S, Ranki A, Kere J, Lehto M, Notarangelo LD, Nejentsev S, Eklund KK, Varjosalo M, Taipale J, Seppänen MRJ. Göös H, et al. Among authors: vaarala o. J Allergy Clin Immunol. 2019 Nov;144(5):1364-1376. doi: 10.1016/j.jaci.2019.06.003. Epub 2019 Jun 13. J Allergy Clin Immunol. 2019. PMID: 31201888 Free PMC article.
Patients with type 1 diabetes show signs of vascular dysfunction in response to multiple high-fat meals.
Lassenius MI, Mäkinen VP, Fogarty CL, Peräneva L, Jauhiainen M, Pussinen PJ, Taskinen MR, Kirveskari J, Vaarala O, Nieminen JK, Hörkkö S, Kangas AJ, Soininen P, Ala-Korpela M, Gordin D, Ahola AJ, Forsblom C, Groop PH, Lehto M. Lassenius MI, et al. Among authors: vaarala o. Nutr Metab (Lond). 2014 Jun 13;11:28. doi: 10.1186/1743-7075-11-28. eCollection 2014. Nutr Metab (Lond). 2014. PMID: 24959195 Free PMC article.
High-fat meals induce systemic cytokine release without evidence of endotoxemia-mediated cytokine production from circulating monocytes or myeloid dendritic cells.
Fogarty CL, Nieminen JK, Peräneva L, Lassenius MI, Ahola AJ, Taskinen MR, Jauhiainen M, Kirveskari J, Pussinen P, Hörkkö S, Mäkinen VP, Gordin D, Forsblom C, Groop PH, Vaarala O, Lehto M. Fogarty CL, et al. Among authors: vaarala o. Acta Diabetol. 2015 Apr;52(2):315-22. doi: 10.1007/s00592-014-0641-8. Epub 2014 Sep 3. Acta Diabetol. 2015. PMID: 25182144
Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus.
Hafrén L, Einarsdottir E, Kentala E, Hammarén-Malmi S, Bhutta MF, MacArthur CJ, Wilmot B, Casselbrant M, Conley YP, Weeks DE, Mandel EM, Vaarala O, Kallio A, Melin M, Nieminen JK, Leinonen E, Kere J, Mattila PS. Hafrén L, et al. Among authors: vaarala o. PLoS One. 2015 Jul 15;10(7):e0132551. doi: 10.1371/journal.pone.0132551. eCollection 2015. PLoS One. 2015. PMID: 26177520 Free PMC article.
Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation.
Jevnikar Z, Östling J, Ax E, Calvén J, Thörn K, Israelsson E, Öberg L, Singhania A, Lau LCK, Wilson SJ, Ward JA, Chauhan A, Sousa AR, De Meulder B, Loza MJ, Baribaud F, Sterk PJ, Chung KF, Sun K, Guo Y, Adcock IM, Payne D, Dahlen B, Chanez P, Shaw DE, Krug N, Hohlfeld JM, Sandström T, Djukanovic R, James A, Hinks TSC, Howarth PH, Vaarala O, van Geest M, Olsson H; Unbiased Biomarkers in Prediction of Respiratory Disease Outcomes study group. Jevnikar Z, et al. Among authors: vaarala o. J Allergy Clin Immunol. 2019 Feb;143(2):577-590. doi: 10.1016/j.jaci.2018.05.026. Epub 2018 Jun 11. J Allergy Clin Immunol. 2019. PMID: 29902480 Free article.
IL-17-high asthma with features of a psoriasis immunophenotype.
Östling J, van Geest M, Schofield JPR, Jevnikar Z, Wilson S, Ward J, Lutter R, Shaw DE, Bakke PS, Caruso M, Dahlen SE, Fowler SJ, Horváth I, Krug N, Montuschi P, Sanak M, Sandström T, Sun K, Pandis I, Auffray C, Sousa AR, Guo Y, Adcock IM, Howarth P, Chung KF, Bigler J, Sterk PJ, Skipp PJ, Djukanović R, Vaarala O; U-BIOPRED Study Group. Östling J, et al. Among authors: vaarala o. J Allergy Clin Immunol. 2019 Nov;144(5):1198-1213. doi: 10.1016/j.jaci.2019.03.027. Epub 2019 Apr 15. J Allergy Clin Immunol. 2019. PMID: 30998987 Free article. Clinical Trial.
Fungal Dysbiosis and Intestinal Inflammation in Children With Beta-Cell Autoimmunity.
Honkanen J, Vuorela A, Muthas D, Orivuori L, Luopajärvi K, Tejesvi MVG, Lavrinienko A, Pirttilä AM, Fogarty CL, Härkönen T, Ilonen J, Ruohtula T, Knip M, Koskimäki JJ, Vaarala O. Honkanen J, et al. Among authors: vaarala o. Front Immunol. 2020 Mar 19;11:468. doi: 10.3389/fimmu.2020.00468. eCollection 2020. Front Immunol. 2020. PMID: 32265922 Free PMC article.
276 results