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Impairments in contractility and cytoskeletal organisation cause nuclear defects in nemaline myopathy.
Ross JA, Levy Y, Ripolone M, Kolb JS, Turmaine M, Holt M, Lindqvist J, Claeys KG, Weis J, Monforte M, Tasca G, Moggio M, Figeac N, Zammit PS, Jungbluth H, Fiorillo C, Vissing J, Witting N, Granzier H, Zanoteli E, Hardeman EC, Wallgren-Pettersson C, Ochala J. Ross JA, et al. Among authors: ochala j. Acta Neuropathol. 2019 Sep;138(3):477-495. doi: 10.1007/s00401-019-02034-8. Epub 2019 Jun 19. Acta Neuropathol. 2019. PMID: 31218456 Free PMC article.
Physical activity impacts resting skeletal muscle myosin conformation and lowers its ATP consumption.
Lewis CTA, Tabrizian L, Nielsen J, Laitila J, Beck TN, Olsen MS, Ognjanovic MM, Aagaard P, Hokken R, Laugesen S, Ingersen A, Andersen JL, Soendenbroe C, Helge JW, Dela F, Larsen S, Sahl RE, Rømer T, Hansen MT, Frandsen J, Suetta C, Ochala J. Lewis CTA, et al. Among authors: ochala j. J Gen Physiol. 2023 Jul 3;155(7):e202213268. doi: 10.1085/jgp.202213268. Epub 2023 May 25. J Gen Physiol. 2023. PMID: 37227464 Free PMC article.
Remodelling of Skeletal Muscle Myosin Metabolic States in Hibernating Mammals.
Lewis CTA, Melhedegaard EG, Ognjanovic MM, Olsen MS, Laitila J, Seaborne RAE, Gronset MN, Zhang C, Iwamoto H, Hessel AL, Kuehn MN, Merino C, Amigo N, Frobert O, Giroud S, Staples JF, Goropashnaya AV, Fedorov VB, Barnes BM, Toien O, Drew KL, Sprenger RJ, Ochala J. Lewis CTA, et al. Among authors: ochala j. bioRxiv [Preprint]. 2024 Feb 27:2023.11.14.566992. doi: 10.1101/2023.11.14.566992. bioRxiv. 2024. Update in: Elife. 2024 May 16;13:RP94616. doi: 10.7554/eLife.94616 PMID: 38014200 Free PMC article. Updated. Preprint.
A myopathy-related actin mutation increases contractile function.
Lindqvist J, Pénisson-Besnier I, Iwamoto H, Li M, Yagi N, Ochala J. Lindqvist J, et al. Among authors: ochala j. Acta Neuropathol. 2012 May;123(5):739-46. doi: 10.1007/s00401-012-0962-z. Epub 2012 Feb 23. Acta Neuropathol. 2012. PMID: 22358459
92 results