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HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma.
Faião-Flores F, Emmons MF, Durante MA, Kinose F, Saha B, Fang B, Koomen JM, Chellappan SP, Maria-Engler SS, Rix U, Licht JD, Harbour JW, Smalley KSM. Faião-Flores F, et al. Among authors: licht jd. Clin Cancer Res. 2019 Sep 15;25(18):5686-5701. doi: 10.1158/1078-0432.CCR-18-3382. Epub 2019 Jun 21. Clin Cancer Res. 2019. PMID: 31227503 Free PMC article.
Decitabine limits escape from MEK inhibition in uveal melanoma.
Gonçalves J, Emmons MF, Faião-Flores F, Aplin AE, Harbour JW, Licht JD, Wink MR, Smalley KSM. Gonçalves J, et al. Among authors: licht jd. Pigment Cell Melanoma Res. 2020 May;33(3):507-514. doi: 10.1111/pcmr.12849. Epub 2019 Dec 6. Pigment Cell Melanoma Res. 2020. PMID: 31758842 Free PMC article.
DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks.
Venugopal K, Feng Y, Nowialis P, Xu H, Shabashvili DE, Berntsen CM, Kaur P, Krajcik KI, Taragjini C, Zaroogian Z, Casellas Román HL, Posada LM, Gunaratne C, Li J, Dupéré-Richer D, Bennett RL, Pondugula S, Riva A, Cogle CR, Opavsky R, Law BK, Bhaduri-McIntosh S, Kubicek S, Staber PB, Licht JD, Bird JE, Guryanova OA. Venugopal K, et al. Among authors: licht jd. Clin Cancer Res. 2022 Feb 15;28(4):756-769. doi: 10.1158/1078-0432.CCR-21-2863. Clin Cancer Res. 2022. PMID: 34716195 Free PMC article.
HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma.
Sriramareddy SN, Faião-Flores F, Emmons MF, Saha B, Chellappan S, Wyatt C, Smalley I, Licht JD, Durante MA, Harbour JW, Smalley KSM. Sriramareddy SN, et al. Among authors: licht jd. Cancer Gene Ther. 2022 Dec;29(12):1840-1846. doi: 10.1038/s41417-022-00452-7. Epub 2022 Mar 24. Cancer Gene Ther. 2022. PMID: 35332245 Free PMC article.
235 results