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Resting-State Functional Connectivity Is Associated With Cerebrospinal Fluid Levels of the Synaptic Protein NPTX2 in Non-demented Older Adults.
Soldan A, Moghekar A, Walker KA, Pettigrew C, Hou X, Lu H, Miller MI, Alfini A, Albert M, Xu D, Xiao MF, Worley P; BIOCARD Research Team. Soldan A, et al. Among authors: xu d. Front Aging Neurosci. 2019 Jun 7;11:132. doi: 10.3389/fnagi.2019.00132. eCollection 2019. Front Aging Neurosci. 2019. PMID: 31231205 Free PMC article.
Cerebrospinal fluid profile of NPTX2 supports role of Alzheimer's disease-related inhibitory circuit dysfunction in adults with Down syndrome.
Belbin O, Xiao MF, Xu D, Carmona-Iragui M, Pegueroles J, Benejam B, Videla L, Fernández S, Barroeta I, Nuñez-Llaves R, Montal V, Vilaplana E, Altuna M, Clarimón J, Alcolea D, Blesa R, Lleó A, Worley PF, Fortea J. Belbin O, et al. Among authors: xu d. Mol Neurodegener. 2020 Aug 17;15(1):46. doi: 10.1186/s13024-020-00398-0. Mol Neurodegener. 2020. PMID: 32807227 Free PMC article.
NPTX2 and cognitive dysfunction in Alzheimer's Disease.
Xiao MF, Xu D, Craig MT, Pelkey KA, Chien CC, Shi Y, Zhang J, Resnick S, Pletnikova O, Salmon D, Brewer J, Edland S, Wegiel J, Tycko B, Savonenko A, Reeves RH, Troncoso JC, McBain CJ, Galasko D, Worley PF. Xiao MF, et al. Among authors: xu d. Elife. 2017 Mar 23;6:e23798. doi: 10.7554/eLife.23798. Elife. 2017. PMID: 28440221 Free PMC article.
Identification of novel cerebrospinal fluid biomarker candidates for dementia with Lewy bodies: a proteomic approach.
van Steenoven I, Koel-Simmelink MJA, Vergouw LJM, Tijms BM, Piersma SR, Pham TV, Bridel C, Ferri GL, Cocco C, Noli B, Worley PF, Xiao MF, Xu D, Oeckl P, Otto M, van der Flier WM, de Jong FJ, Jimenez CR, Lemstra AW, Teunissen CE. van Steenoven I, et al. Among authors: xu d. Mol Neurodegener. 2020 Jun 18;15(1):36. doi: 10.1186/s13024-020-00388-2. Mol Neurodegener. 2020. PMID: 32552841 Free PMC article.
A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function.
Xiao MF, Roh SE, Zhou J, Chien CC, Lucey BP, Craig MT, Hayes LN, Coughlin JM, Leweke FM, Jia M, Xu D, Zhou W, Conover Talbot C Jr, Arnold DB, Staley M, Jiang C, Reti IM, Sawa A, Pelkey KA, McBain CJ, Savonenko A, Worley PF. Xiao MF, et al. Among authors: xu d. Sci Adv. 2021 Nov 26;7(48):eabf6935. doi: 10.1126/sciadv.abf6935. Epub 2021 Nov 24. Sci Adv. 2021. PMID: 34818031 Free PMC article.
Synaptic biomarkers in CSF aid in diagnosis, correlate with cognition and predict progression in MCI and Alzheimer's disease.
Galasko D, Xiao M, Xu D, Smirnov D, Salmon DP, Dewit N, Vanbrabant J, Jacobs D, Vanderstichele H, Vanmechelen E; Alzheimer's Disease Neuroimaging Initiative (ADNI); Worley P. Galasko D, et al. Among authors: xu d. Alzheimers Dement (N Y). 2019 Dec 9;5:871-882. doi: 10.1016/j.trci.2019.11.002. eCollection 2019. Alzheimers Dement (N Y). 2019. PMID: 31853477 Free PMC article.
VAMP-2 is a surrogate cerebrospinal fluid marker of Alzheimer-related cognitive impairment in adults with Down syndrome.
Lleó A, Carmona-Iragui M, Videla L, Fernández S, Benejam B, Pegueroles J, Barroeta I, Altuna M, Valldeneu S, Xiao MF, Xu D, Núñez-Llaves R, Querol-Vilaseca M, Sirisi S, Bejanin A, Iulita MF, Clarimón J, Blesa R, Worley P, Alcolea D, Fortea J, Belbin O. Lleó A, et al. Among authors: xu d. Alzheimers Res Ther. 2021 Jun 28;13(1):119. doi: 10.1186/s13195-021-00861-0. Alzheimers Res Ther. 2021. PMID: 34183050 Free PMC article.
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