Hunter WN - Search Results

1

Burkholderia pseudomallei d-alanine-d-alanine ligase; detailed characterisation and assessment of a potential antibiotic drug target.

Díaz-Sáez L, Torrie LS, McElroy SP, Gray D, Hunter WN. Díaz-Sáez L, et al. Among authors: hunter wn. FEBS J. 2019 Nov;286(22):4509-4524. doi: 10.1111/febs.14976. Epub 2019 Jul 16. FEBS J. 2019. PMID: 31260169 Free PMC article.

2

The crystal structure of a plant 2C-methyl-D-erythritol 4-phosphate cytidylyltransferase exhibits a distinct quaternary structure compared to bacterial homologues and a possible role in feedback regulation for cytidine monophosphate.

Gabrielsen M, Kaiser J, Rohdich F, Eisenreich W, Laupitz R, Bacher A, Bond CS, Hunter WN. Gabrielsen M, et al. Among authors: hunter wn. FEBS J. 2006 Mar;273(5):1065-73. doi: 10.1111/j.1742-4658.2006.05133.x. FEBS J. 2006. PMID: 16478479 Free article.

3

Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates.

Sundaramoorthy R, Iulek J, Barrett MP, Bidet O, Ruda GF, Gilbert IH, Hunter WN. Sundaramoorthy R, et al. Among authors: hunter wn. FEBS J. 2007 Jan;274(1):275-86. doi: 10.1111/j.1742-4658.2006.05585.x. FEBS J. 2007. PMID: 17222187 Free PMC article.

4

Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery.

Sgraja T, Alphey MS, Ghilagaber S, Marquez R, Robertson MN, Hemmings JL, Lauw S, Rohdich F, Bacher A, Eisenreich W, Illarionova V, Hunter WN. Sgraja T, et al. Among authors: hunter wn. FEBS J. 2008 Jun;275(11):2779-94. doi: 10.1111/j.1742-4658.2008.06418.x. Epub 2008 Apr 16. FEBS J. 2008. PMID: 18422643 Free PMC article.

5

Structure of Staphylococcus aureus adenylosuccinate lyase (PurB) and assessment of its potential as a target for structure-based inhibitor discovery.

Fyfe PK, Dawson A, Hutchison MT, Cameron S, Hunter WN. Fyfe PK, et al. Among authors: hunter wn. Acta Crystallogr D Biol Crystallogr. 2010 Aug;66(Pt 8):881-8. doi: 10.1107/S0907444910020081. Epub 2010 Jul 9. Acta Crystallogr D Biol Crystallogr. 2010. PMID: 20693687 Free PMC article.

6

Assessment of Pseudomonas aeruginosa N5,N10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase as a potential antibacterial drug target.

Eadsforth TC, Gardiner M, Maluf FV, McElroy S, James D, Frearson J, Gray D, Hunter WN. Eadsforth TC, et al. Among authors: hunter wn. PLoS One. 2012;7(4):e35973. doi: 10.1371/journal.pone.0035973. Epub 2012 Apr 25. PLoS One. 2012. PMID: 22558288 Free PMC article.

7

IspE inhibitors identified by a combination of in silico and in vitro high-throughput screening.

Tidten-Luksch N, Grimaldi R, Torrie LS, Frearson JA, Hunter WN, Brenk R. Tidten-Luksch N, et al. Among authors: hunter wn. PLoS One. 2012;7(4):e35792. doi: 10.1371/journal.pone.0035792. Epub 2012 Apr 25. PLoS One. 2012. PMID: 22563402 Free PMC article.

8

Acinetobacter baumannii FolD ligand complexes --potent inhibitors of folate metabolism and a re-evaluation of the structure of LY374571.

Eadsforth TC, Maluf FV, Hunter WN. Eadsforth TC, et al. Among authors: hunter wn. FEBS J. 2012 Dec;279(23):4350-60. doi: 10.1111/febs.12025. Epub 2012 Nov 5. FEBS J. 2012. PMID: 23050773 Free PMC article.

9

The architecture of Trypanosoma brucei tubulin-binding cofactor B and implications for function.

Fleming JR, Morgan RE, Fyfe PK, Kelly SM, Hunter WN. Fleming JR, et al. Among authors: hunter wn. FEBS J. 2013 Jul;280(14):3270-80. doi: 10.1111/febs.12308. Epub 2013 May 24. FEBS J. 2013. PMID: 23627368 Free PMC article.

10

Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessment.

O'Rourke PE, Kalinowska-Tłuścik J, Fyfe PK, Dawson A, Hunter WN. O'Rourke PE, et al. Among authors: hunter wn. BMC Struct Biol. 2014 Jan 10;14:1. doi: 10.1186/1472-6807-14-1. BMC Struct Biol. 2014. PMID: 24410837 Free PMC article.

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