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Sequential LASER ART and CRISPR Treatments Eliminate HIV-1 in a Subset of Infected Humanized Mice.
Dash PK, Kaminski R, Bella R, Su H, Mathews S, Ahooyi TM, Chen C, Mancuso P, Sariyer R, Ferrante P, Donadoni M, Robinson JA, Sillman B, Lin Z, Hilaire JR, Banoub M, Elango M, Gautam N, Mosley RL, Poluektova LY, McMillan J, Bade AN, Gorantla S, Sariyer IK, Burdo TH, Young WB, Amini S, Gordon J, Jacobson JM, Edagwa B, Khalili K, Gendelman HE. Dash PK, et al. Among authors: lin z. Nat Commun. 2019 Jul 2;10(1):2753. doi: 10.1038/s41467-019-10366-y. Nat Commun. 2019. PMID: 31266936 Free PMC article.
Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles.
Zhou T, Su H, Dash P, Lin Z, Dyavar Shetty BL, Kocher T, Szlachetka A, Lamberty B, Fox HS, Poluektova L, Gorantla S, McMillan J, Gautam N, Mosley RL, Alnouti Y, Edagwa B, Gendelman HE. Zhou T, et al. Among authors: lin z. Biomaterials. 2018 Jan;151:53-65. doi: 10.1016/j.biomaterials.2017.10.023. Epub 2017 Oct 15. Biomaterials. 2018. PMID: 29059541 Free PMC article.
Antiretroviral Drug Metabolism in Humanized PXR-CAR-CYP3A-NOG Mice.
McMillan JM, Cobb DA, Lin Z, Banoub MG, Dagur RS, Branch Woods AA, Wang W, Makarov E, Kocher T, Joshi PS, Quadros RM, Harms DW, Cohen SM, Gendelman HE, Gurumurthy CB, Gorantla S, Poluektova LY. McMillan JM, et al. Among authors: lin z. J Pharmacol Exp Ther. 2018 May;365(2):272-280. doi: 10.1124/jpet.117.247288. Epub 2018 Feb 23. J Pharmacol Exp Ther. 2018. PMID: 29476044 Free PMC article.
Optimizing the preparation and stability of decorated antiretroviral drug nanocrystals.
Zhou T, Lin Z, Puligujja P, Palandri D, Hilaire J, Araínga M, Smith N, Gautam N, McMillan J, Alnouti Y, Liu X, Edagwa B, Gendelman HE. Zhou T, et al. Among authors: lin z. Nanomedicine (Lond). 2018 Apr;13(8):871-885. doi: 10.2217/nnm-2017-0381. Epub 2018 Mar 19. Nanomedicine (Lond). 2018. PMID: 29553879 Free PMC article.
ProTide generated long-acting abacavir nanoformulations.
Lin Z , Gautam N , Alnouti Y , McMillan J , Bade AN , Gendelman HE , Edagwa B . Lin Z , et al. Chem Commun (Camb). 2018 Jul 24;54(60):8371-8374. doi: 10.1039/c8cc04708a. Chem Commun (Camb). 2018. PMID: 29995046 Free PMC article.
Modulating cellular autophagy for controlled antiretroviral drug release.
Thomas MB, Gnanadhas DP, Dash PK, Machhi J, Lin Z, McMillan J, Edagwa B, Gelbard H, Gendelman HE, Gorantla S. Thomas MB, et al. Among authors: lin z. Nanomedicine (Lond). 2018 Sep;13(17):2139-2154. doi: 10.2217/nnm-2018-0224. Epub 2018 Aug 21. Nanomedicine (Lond). 2018. PMID: 30129397 Free PMC article.
Synthesis and characterization of a long-acting emtricitabine prodrug nanoformulation.
Ibrahim IM, Bade AN, Lin Z, Soni D, Wojtkiewicz M, Dyavar Shetty BL, Gautam N, McMillan JM, Alnouti Y, Edagwa BJ, Gendelman HE. Ibrahim IM, et al. Among authors: lin z. Int J Nanomedicine. 2019 Aug 7;14:6231-6247. doi: 10.2147/IJN.S215447. eCollection 2019. Int J Nanomedicine. 2019. PMID: 31496683 Free PMC article.
Synthesis and Characterization of Long-Acting Darunavir Prodrugs.
Banoub MG, Bade AN, Lin Z, Cobb D, Gautam N, Dyavar Shetty BL, Wojtkiewicz M, Alnouti Y, McMillan J, Gendelman HE, Edagwa B. Banoub MG, et al. Among authors: lin z. Mol Pharm. 2020 Jan 6;17(1):155-166. doi: 10.1021/acs.molpharmaceut.9b00871. Epub 2019 Dec 3. Mol Pharm. 2020. PMID: 31742407 Free PMC article.
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