Deprez B - Search Results

1

Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening.

Leroux F, Bosc D, Beghyn T, Hermant P, Warenghem S, Landry V, Pottiez V, Guillaume V, Charton J, Herledan A, Urata S, Liang W, Sheng L, Tang WJ, Deprez B, Deprez-Poulain R. Leroux F, et al. Among authors: deprez poulain r, deprez b. Eur J Med Chem. 2019 Oct 1;179:557-566. doi: 10.1016/j.ejmech.2019.06.057. Epub 2019 Jun 24. Eur J Med Chem. 2019. PMID: 31276900 Free PMC article.

2

Facts, figures and trends in lead generation.

Deprez-Poulain R, Deprez B. Deprez-Poulain R, et al. Among authors: deprez b. Curr Top Med Chem. 2004;4(6):569-80. doi: 10.2174/1568026043451168. Curr Top Med Chem. 2004. PMID: 14965294 Review.

3

A library of novel hydroxamic acids targeting the metallo-protease family: design, parallel synthesis and screening.

Flipo M, Beghyn T, Charton J, Leroux VA, Deprez BP, Deprez-Poulain RF. Flipo M, et al. Bioorg Med Chem. 2007 Jan 1;15(1):63-76. doi: 10.1016/j.bmc.2006.10.010. Epub 2006 Oct 12. Bioorg Med Chem. 2007. PMID: 17070058

4

PDE5 inhibitors: An original access to novel potent arylated analogues of tadalafil.

Beghyn T, Hounsou C, Deprez BP. Beghyn T, et al. Bioorg Med Chem Lett. 2007 Feb 1;17(3):789-92. doi: 10.1016/j.bmcl.2006.10.069. Epub 2006 Oct 27. Bioorg Med Chem Lett. 2007. PMID: 17107795

5

Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents.

Flipo M, Beghyn T, Leroux V, Florent I, Deprez BP, Deprez-Poulain RF. Flipo M, et al. J Med Chem. 2007 Mar 22;50(6):1322-34. doi: 10.1021/jm061169b. Epub 2007 Feb 28. J Med Chem. 2007. PMID: 17326615

6

Alkylsquarates as key intermediates for the rapid preparation of original drug-inspired compounds.

Charton J, Charruault L, Deprez-Poulain R, Deprez B. Charton J, et al. Among authors: deprez poulain r, deprez b. Comb Chem High Throughput Screen. 2008 May;11(4):294-303. doi: 10.2174/138620708784246013. Comb Chem High Throughput Screen. 2008. PMID: 18473739

7

Natural compounds: leads or ideas? Bioinspired molecules for drug discovery.

Beghyn T, Deprez-Poulain R, Willand N, Folleas B, Deprez B. Beghyn T, et al. Among authors: deprez poulain r, deprez b. Chem Biol Drug Des. 2008 Jul;72(1):3-15. doi: 10.1111/j.1747-0285.2008.00673.x. Epub 2008 Jun 11. Chem Biol Drug Des. 2008. PMID: 18554253

8

Synthesis of a 200-member library of squaric acid N-hydroxylamide amides.

Charton J, Leroux F, Delaroche S, Landry V, Déprez BP, Déprez-Poulain RF. Charton J, et al. Bioorg Med Chem Lett. 2008 Sep 15;18(18):4968-71. doi: 10.1016/j.bmcl.2008.08.025. Epub 2008 Aug 14. Bioorg Med Chem Lett. 2008. PMID: 18760922

9

Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.

Charton J, Deprez-Poulain R, Hennuyer N, Tailleux A, Staels B, Deprez B. Charton J, et al. Among authors: deprez poulain r, deprez b. Bioorg Med Chem Lett. 2009 Jan 15;19(2):489-92. doi: 10.1016/j.bmcl.2008.11.040. Epub 2008 Nov 18. Bioorg Med Chem Lett. 2009. PMID: 19058965 Free article.

10

Synthetic EthR inhibitors boost antituberculous activity of ethionamide.

Willand N, Dirié B, Carette X, Bifani P, Singhal A, Desroses M, Leroux F, Willery E, Mathys V, Déprez-Poulain R, Delcroix G, Frénois F, Aumercier M, Locht C, Villeret V, Déprez B, Baulard AR. Willand N, et al. Among authors: deprez poulain r, deprez b. Nat Med. 2009 May;15(5):537-44. doi: 10.1038/nm.1950. Epub 2009 May 3. Nat Med. 2009. PMID: 19412174

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