Falk BT - Search Results

1

NMR Assessment of Therapeutic Peptides and Proteins: Correlations That Reveal Interactions and Motions.

Falk BT, Liang Y, Bailly M, Raoufi F, Kekec A, Pissarnitski D, Feng D, Yan L, Lin S, Fayadat-Dilman L, McCoy MA. Falk BT, et al. Chembiochem. 2020 Feb 3;21(3):315-319. doi: 10.1002/cbic.201900296. Epub 2019 Oct 24. Chembiochem. 2020. PMID: 31283075

2

Diffusion Profiling of Therapeutic Proteins by Using Solution NMR Spectroscopy.

Falk BT, Liang Y, McCoy MA. Falk BT, et al. Chembiochem. 2019 Apr 1;20(7):896-899. doi: 10.1002/cbic.201800631. Epub 2019 Mar 4. Chembiochem. 2019. PMID: 30515922

3

Profiling Insulin Oligomeric States by ¹H NMR Spectroscopy for Formulation Development of Ultra-Rapid-Acting Insulin.

Falk BT, Liang Y, McCoy MA. Falk BT, et al. J Pharm Sci. 2020 Jan;109(1):922-926. doi: 10.1016/j.xphs.2019.07.025. Epub 2019 Aug 23. J Pharm Sci. 2020. PMID: 31449814

4

Investigating protein-excipient interactions of a multivalent V_HH therapeutic protein using NMR spectroscopy.

Panchal J, Falk BT, Antochshuk V, McCoy MA. Panchal J, et al. Among authors: falk bt. MAbs. 2022 Jan-Dec;14(1):2124902. doi: 10.1080/19420862.2022.2124902. MAbs. 2022. PMID: 36166705 Free PMC article.

5

Molecular Mechanism of Antimicrobial Excipient-Induced Aggregation in Parenteral Formulations of Peptide Therapeutics.

Li M, Falk BT, Lu X, Schroder R, Mccoy M, Xu W, Yin DH, Gindy ME, D'Addio SM, Su Y. Li M, et al. Among authors: falk bt. Mol Pharm. 2022 Sep 5;19(9):3267-3278. doi: 10.1021/acs.molpharmaceut.2c00449. Epub 2022 Aug 2. Mol Pharm. 2022. PMID: 35917158

6

Chemical shift imprint of intersubunit communication in a symmetric homodimer.

Falk BT, Sapienza PJ, Lee AL. Falk BT, et al. Proc Natl Acad Sci U S A. 2016 Aug 23;113(34):9533-8. doi: 10.1073/pnas.1604748113. Epub 2016 Jul 27. Proc Natl Acad Sci U S A. 2016. PMID: 27466406 Free PMC article.

7

Bacterial Thymidylate Synthase Binds Two Molecules of Substrate and Cofactor without Cooperativity.

Sapienza PJ, Falk BT, Lee AL. Sapienza PJ, et al. Among authors: falk bt. J Am Chem Soc. 2015 Nov 18;137(45):14260-3. doi: 10.1021/jacs.5b10128. Epub 2015 Nov 9. J Am Chem Soc. 2015. PMID: 26517288 Free PMC article.

8

Inter-Active Site Communication Mediated by the Dimer Interface β-Sheet in the Half-the-Sites Enzyme, Thymidylate Synthase.

Sapienza PJ, Popov KI, Mowrey DD, Falk BT, Dokholyan NV, Lee AL. Sapienza PJ, et al. Among authors: falk bt. Biochemistry. 2019 Jul 30;58(30):3302-3313. doi: 10.1021/acs.biochem.9b00486. Epub 2019 Jul 18. Biochemistry. 2019. PMID: 31283187 Free PMC article.

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