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Page 1
HIF-1α is over-expressed in leukemic cells from TP53-disrupted patients and is a promising therapeutic target in chronic lymphocytic leukemia.
Griggio V, Vitale C, Todaro M, Riganti C, Kopecka J, Salvetti C, Bomben R, Bo MD, Magliulo D, Rossi D, Pozzato G, Bonello L, Marchetti M, Omedè P, Kodipad AA, Laurenti L, Del Poeta G, Mauro FR, Bernardi R, Zenz T, Gattei V, Gaidano G, Foà R, Massaia M, Boccadoro M, Coscia M. Griggio V, et al. Haematologica. 2020 Apr;105(4):1042-1054. doi: 10.3324/haematol.2019.217430. Epub 2019 Jul 9. Haematologica. 2020. PMID: 31289209 Free PMC article.
IGHV unmutated CLL B cells are more prone to spontaneous apoptosis and subject to environmental prosurvival signals than mutated CLL B cells.
Coscia M, Pantaleoni F, Riganti C, Vitale C, Rigoni M, Peola S, Castella B, Foglietta M, Griggio V, Drandi D, Ladetto M, Bosia A, Boccadoro M, Massaia M. Coscia M, et al. Among authors: griggio v. Leukemia. 2011 May;25(5):828-37. doi: 10.1038/leu.2011.12. Epub 2011 Mar 4. Leukemia. 2011. PMID: 21372840 Free article.
Dysfunctional Vγ9Vδ2 T cells are negative prognosticators and markers of dysregulated mevalonate pathway activity in chronic lymphocytic leukemia cells.
Coscia M, Vitale C, Peola S, Foglietta M, Rigoni M, Griggio V, Castella B, Angelini D, Chiaretti S, Riganti C, Guarini A, Drandi D, Ladetto M, Bosia A, Foà R, Battistini L, Boccadoro M, Fournié JJ, Massaia M. Coscia M, et al. Among authors: griggio v. Blood. 2012 Oct 18;120(16):3271-9. doi: 10.1182/blood-2012-03-417519. Epub 2012 Aug 29. Blood. 2012. PMID: 22932792 Free article.
Simvastatin and downstream inhibitors circumvent constitutive and stromal cell-induced resistance to doxorubicin in IGHV unmutated CLL cells.
Rigoni M, Riganti C, Vitale C, Griggio V, Campia I, Robino M, Foglietta M, Castella B, Sciancalepore P, Buondonno I, Drandi D, Ladetto M, Boccadoro M, Massaia M, Coscia M. Rigoni M, et al. Among authors: griggio v. Oncotarget. 2015 Oct 6;6(30):29833-46. doi: 10.18632/oncotarget.4006. Oncotarget. 2015. PMID: 26284584 Free PMC article.
Anergic bone marrow Vγ9Vδ2 T cells as early and long-lasting markers of PD-1-targetable microenvironment-induced immune suppression in human myeloma.
Castella B, Foglietta M, Sciancalepore P, Rigoni M, Coscia M, Griggio V, Vitale C, Ferracini R, Saraci E, Omedé P, Riganti C, Palumbo A, Boccadoro M, Massaia M. Castella B, et al. Among authors: griggio v. Oncoimmunology. 2015 May 26;4(11):e1047580. doi: 10.1080/2162402X.2015.1047580. eCollection 2015 Nov. Oncoimmunology. 2015. PMID: 26451323 Free PMC article.
Humoral immune responses toward tumor-derived antigens in previously untreated patients with chronic lymphocytic leukemia.
Griggio V, Mandili G, Vitale C, Capello M, Macor P, Serra S, Castella B, Peola S, Foglietta M, Drandi D, Omedé P, Sblattero D, Cappello P, Chiarle R, Deaglio S, Boccadoro M, Novelli F, Massaia M, Coscia M. Griggio V, et al. Oncotarget. 2017 Jan 10;8(2):3274-3288. doi: 10.18632/oncotarget.13712. Oncotarget. 2017. PMID: 27906678 Free PMC article.
Magic pills: new oral drugs to treat chronic lymphocytic leukemia.
Vitale C, Griggio V, Todaro M, Salvetti C, Boccadoro M, Coscia M. Vitale C, et al. Among authors: griggio v. Expert Opin Pharmacother. 2017 Mar;18(4):411-425. doi: 10.1080/14656566.2017.1293655. Epub 2017 Feb 22. Expert Opin Pharmacother. 2017. PMID: 28234562 Review.
Preexisting and treatment-emergent autoimmune cytopenias in patients with CLL treated with targeted drugs.
Vitale C, Salvetti C, Griggio V, Porrazzo M, Schiattone L, Zamprogna G, Visentin A, Vassallo F, Cassin R, Rigolin GM, Murru R, Laurenti L, Rivela P, Marchetti M, Pennese E, Gentile M, Boccellato E, Perutelli F, Montalbano MC, De Paoli L, Reda G, Orsucci L, Trentin L, Cuneo A, Tedeschi A, Scarfò L, Gaidano G, Mauro FR, Foà R, Boccadoro M, Coscia M. Vitale C, et al. Among authors: griggio v. Blood. 2021 Jun 24;137(25):3507-3517. doi: 10.1182/blood.2020008201. Blood. 2021. PMID: 33651883 Free article. Clinical Trial.
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