Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

46,413 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Misfolded proinsulin impairs processing of precursor of insulin receptor and insulin signaling in β cells.
Liu S, Li X, Yang J, Zhu R, Fan Z, Xu X, Feng W, Cui J, Sun J, Liu M. Liu S, et al. Among authors: liu m. FASEB J. 2019 Oct;33(10):11338-11348. doi: 10.1096/fj.201900442R. Epub 2019 Aug 1. FASEB J. 2019. PMID: 31311313 Free PMC article.
These results reveal for the first time that misfolded proinsulin can interact with ProIR in the ER, impairing intracellular processing of ProIR and leading to defective insulin signaling that may contribute to beta-cell failure in both MIDY and T2D.-Liu, S., Li, X., Yang, …
These results reveal for the first time that misfolded proinsulin can interact with ProIR in the ER, impairing intracellular processing of P …
Proinsulin maturation, misfolding, and proteotoxicity.
Liu M, Hodish I, Rhodes CJ, Arvan P. Liu M, et al. Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15841-6. doi: 10.1073/pnas.0702697104. Epub 2007 Sep 26. Proc Natl Acad Sci U S A. 2007. PMID: 17898179 Free PMC article.
Misfolded proinsulin affects bystander proinsulin in neonatal diabetes.
Hodish I, Liu M, Rajpal G, Larkin D, Holz RW, Adams A, Liu L, Arvan P. Hodish I, et al. Among authors: liu m, liu l. J Biol Chem. 2010 Jan 1;285(1):685-94. doi: 10.1074/jbc.M109.038042. Epub 2009 Oct 30. J Biol Chem. 2010. PMID: 19880509 Free PMC article.
It has previously been shown that misfolded mutant Akita proinsulin in the endoplasmic reticulum engages directly in protein complexes either with nonmutant proinsulin or with "hProCpepGFP" (human proinsulin bearing emerald-GFP within the C-peptide), impairing the trafficking of …
It has previously been shown that misfolded mutant Akita proinsulin in the endoplasmic reticulum engages directly in protein complexes eithe …
In vivo misfolding of proinsulin below the threshold of frank diabetes.
Hodish I, Absood A, Liu L, Liu M, Haataja L, Larkin D, Al-Khafaji A, Zaki A, Arvan P. Hodish I, et al. Among authors: liu m, liu l. Diabetes. 2011 Aug;60(8):2092-101. doi: 10.2337/db10-1671. Epub 2011 Jun 15. Diabetes. 2011. PMID: 21677281 Free PMC article.
46,413 results
You have reached the last available page of results. Please see the User Guide for more information.