Blundell TL - Search Results

1

Identification and Characterization of Genetic Determinants of Isoniazid and Rifampicin Resistance in Mycobacterium tuberculosis in Southern India.

Munir A, Kumar N, Ramalingam SB, Tamilzhalagan S, Shanmugam SK, Palaniappan AN, Nair D, Priyadarshini P, Natarajan M, Tripathy S, Ranganathan UD, Peacock SJ, Parkhill J, Blundell TL, Malhotra S. Munir A, et al. Among authors: blundell tl. Sci Rep. 2019 Jul 16;9(1):10283. doi: 10.1038/s41598-019-46756-x. Sci Rep. 2019. PMID: 31311987 Free PMC article.

2

CHOPIN: a web resource for the structural and functional proteome of Mycobacterium tuberculosis.

Ochoa-Montaño B, Mohan N, Blundell TL. Ochoa-Montaño B, et al. Among authors: blundell tl. Database (Oxford). 2015 Mar 31;2015:bav026. doi: 10.1093/database/bav026. Print 2015. Database (Oxford). 2015. PMID: 25833954 Free PMC article.

3

Structure of Mycobacterium thermoresistibile GlgE defines novel conformational states that contribute to the catalytic mechanism.

Mendes V, Blaszczyk M, Maranha A, Empadinhas N, Blundell TL. Mendes V, et al. Among authors: blundell tl. Sci Rep. 2015 Nov 30;5:17144. doi: 10.1038/srep17144. Sci Rep. 2015. PMID: 26616850 Free PMC article.

4

In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity.

Pires DE, Chen J, Blundell TL, Ascher DB. Pires DE, et al. Among authors: blundell tl. Sci Rep. 2016 Jan 22;6:19848. doi: 10.1038/srep19848. Sci Rep. 2016. PMID: 26797105 Free PMC article.

5

mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance.

Pires DE, Blundell TL, Ascher DB. Pires DE, et al. Among authors: blundell tl. Sci Rep. 2016 Jul 7;6:29575. doi: 10.1038/srep29575. Sci Rep. 2016. PMID: 27384129 Free PMC article.

6

Structure-guided, target-based drug discovery - exploiting genome information from HIV to mycobacterial infections.

Malhotra S, Thomas SE, Ochoa Montano B, Blundell TL. Malhotra S, et al. Among authors: blundell tl. Postepy Biochem. 2016;62(3):262-272. Postepy Biochem. 2016. PMID: 28132480 Review. English.

7

Genomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistance.

Pandurangan AP, Ascher DB, Thomas SE, Blundell TL. Pandurangan AP, et al. Among authors: blundell tl. Biochem Soc Trans. 2017 Apr 15;45(2):303-311. doi: 10.1042/BST20160422. Biochem Soc Trans. 2017. PMID: 28408471 Free PMC article. Review.

8

Structural Biology and the Design of New Therapeutics: From HIV and Cancer to Mycobacterial Infections: A Paper Dedicated to John Kendrew.

Thomas SE, Mendes V, Kim SY, Malhotra S, Ochoa-Montaño B, Blaszczyk M, Blundell TL. Thomas SE, et al. Among authors: blundell tl. J Mol Biol. 2017 Aug 18;429(17):2677-2693. doi: 10.1016/j.jmb.2017.06.014. Epub 2017 Jun 23. J Mol Biol. 2017. PMID: 28648615 Free article. Review.

9

Decoding the similarities and differences among mycobacterial species.

Malhotra S, Vedithi SC, Blundell TL. Malhotra S, et al. Among authors: blundell tl. PLoS Negl Trop Dis. 2017 Aug 30;11(8):e0005883. doi: 10.1371/journal.pntd.0005883. eCollection 2017 Aug. PLoS Negl Trop Dis. 2017. PMID: 28854187 Free PMC article.

10

TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species.

Malhotra S, Mugumbate G, Blundell TL, Higueruelo AP. Malhotra S, et al. Among authors: blundell tl. Database (Oxford). 2017 Jan 1;2017:bax041. doi: 10.1093/database/bax041. Database (Oxford). 2017. PMID: 29220433 Free PMC article.

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