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SF2312 is a natural phosphonate inhibitor of enolase.
Leonard PG, Satani N, Maxwell D, Lin YH, Hammoudi N, Peng Z, Pisaneschi F, Link TM, Lee GR 4th, Sun D, Prasad BAB, Di Francesco ME, Czako B, Asara JM, Wang YA, Bornmann W, DePinho RA, Muller FL. Leonard PG, et al. Among authors: link tm. Nat Chem Biol. 2016 Dec;12(12):1053-1058. doi: 10.1038/nchembio.2195. Epub 2016 Oct 10. Nat Chem Biol. 2016. PMID: 27723749 Free PMC article.
Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors.
Brosey CA, Houl JH, Katsonis P, Balapiti-Modarage LPF, Bommagani S, Arvai A, Moiani D, Bacolla A, Link T, Warden LS, Lichtarge O, Jones DE, Ahmed Z, Tainer JA. Brosey CA, et al. Prog Biophys Mol Biol. 2021 Aug;163:171-186. doi: 10.1016/j.pbiomolbio.2021.02.002. Epub 2021 Feb 23. Prog Biophys Mol Biol. 2021. PMID: 33636189 Free PMC article.
Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas.
Gallardo M, Malaney P, Aitken MJL, Zhang X, Link TM, Shah V, Alybayev S, Wu MH, Pageon LR, Ma H, Jacamo R, Yu L, Xu-Monette ZY, Steinman H, Lee HJ, Sarbassov D, Rapado I, Barton MC, Martinez-Lopez J, Bueso-Ramos C, Young KH, Post SM. Gallardo M, et al. Among authors: link tm. J Natl Cancer Inst. 2020 Jan 1;112(1):95-106. doi: 10.1093/jnci/djz078. J Natl Cancer Inst. 2020. PMID: 31077320 Free PMC article.
Hfq structure, function and ligand binding.
Brennan RG, Link TM. Brennan RG, et al. Among authors: link tm. Curr Opin Microbiol. 2007 Apr;10(2):125-33. doi: 10.1016/j.mib.2007.03.015. Epub 2007 Mar 28. Curr Opin Microbiol. 2007. PMID: 17395525 Review.
Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity.
Mandal PK, Morlacchi P, Knight JM, Link TM, Lee GR 4th, Nurieva R, Singh D, Dhanik A, Kavraki L, Corry DB, Ladbury JE, McMurray JS. Mandal PK, et al. Among authors: link tm. J Med Chem. 2015 Nov 25;58(22):8970-84. doi: 10.1021/acs.jmedchem.5b01321. Epub 2015 Nov 9. J Med Chem. 2015. PMID: 26506089 Free PMC article.
614 results