Loregger A - Search Results

1

Industrial Trans Fatty Acids Stimulate SREBP2-Mediated Cholesterogenesis and Promote Non-Alcoholic Fatty Liver Disease.

Oteng AB, Loregger A, van Weeghel M, Zelcer N, Kersten S. Oteng AB, et al. Among authors: loregger a. Mol Nutr Food Res. 2019 Oct;63(19):e1900385. doi: 10.1002/mnfr.201900385. Epub 2019 Aug 7. Mol Nutr Food Res. 2019. PMID: 31327168 Free PMC article.

2

Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene.

Cook EC, Nelson JK, Sorrentino V, Koenis D, Moeton M, Scheij S, Ottenhoff R, Bleijlevens B, Loregger A, Zelcer N. Cook EC, et al. Among authors: loregger a. PLoS One. 2017 Feb 23;12(2):e0172721. doi: 10.1371/journal.pone.0172721. eCollection 2017. PLoS One. 2017. PMID: 28231341 Free PMC article.

3

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.

Loregger A, Raaben M, Nieuwenhuis J, Tan JME, Jae LT, van den Hengel LG, Hendrix S, van den Berg M, Scheij S, Song JY, Huijbers IJ, Kroese LJ, Ottenhoff R, van Weeghel M, van de Sluis B, Brummelkamp T, Zelcer N. Loregger A, et al. Nat Commun. 2020 Feb 28;11(1):1128. doi: 10.1038/s41467-020-14811-1. Nat Commun. 2020. PMID: 32111832 Free PMC article.

4

The E3 ubiquitin ligase MARCH6 degrades squalene monooxygenase and affects 3-hydroxy-3-methyl-glutaryl coenzyme A reductase and the cholesterol synthesis pathway.

Zelcer N, Sharpe LJ, Loregger A, Kristiana I, Cook EC, Phan L, Stevenson J, Brown AJ. Zelcer N, et al. Among authors: loregger a. Mol Cell Biol. 2014 Apr;34(7):1262-70. doi: 10.1128/MCB.01140-13. Epub 2014 Jan 21. Mol Cell Biol. 2014. PMID: 24449766 Free PMC article.

5

A MARCH6 and IDOL E3 Ubiquitin Ligase Circuit Uncouples Cholesterol Synthesis from Lipoprotein Uptake in Hepatocytes.

Loregger A, Cook EC, Nelson JK, Moeton M, Sharpe LJ, Engberg S, Karimova M, Lambert G, Brown AJ, Zelcer N. Loregger A, et al. Mol Cell Biol. 2015 Nov 2;36(2):285-94. doi: 10.1128/MCB.00890-15. Print 2016 Jan 15. Mol Cell Biol. 2015. PMID: 26527619 Free PMC article.

6

Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake.

Nelson JK, Cook EC, Loregger A, Hoeksema MA, Scheij S, Kovacevic I, Hordijk PL, Ovaa H, Zelcer N. Nelson JK, et al. Among authors: loregger a. J Biol Chem. 2016 Feb 26;291(9):4813-25. doi: 10.1074/jbc.M115.698688. Epub 2015 Dec 30. J Biol Chem. 2016. PMID: 26719329 Free PMC article.

7

FBXW7 regulates endothelial barrier function by suppression of the cholesterol synthesis pathway and prenylation of RhoB.

Pronk MCA, Majolée J, Loregger A, van Bezu JSM, Zelcer N, Hordijk PL, Kovačević I. Pronk MCA, et al. Among authors: loregger a. Mol Biol Cell. 2019 Mar 1;30(5):607-621. doi: 10.1091/mbc.E18-04-0259. Epub 2019 Jan 2. Mol Biol Cell. 2019. PMID: 30601691 Free PMC article.

8

Differential use of E2 ubiquitin conjugating enzymes for regulated degradation of the rate-limiting enzymes HMGCR and SQLE in cholesterol biosynthesis.

Tan JME, Cook ECL, van den Berg M, Scheij S, Zelcer N, Loregger A. Tan JME, et al. Among authors: loregger a. Atherosclerosis. 2019 Feb;281:137-142. doi: 10.1016/j.atherosclerosis.2018.12.008. Epub 2018 Dec 23. Atherosclerosis. 2019. PMID: 30658189 Free article.

9

Assaying Low-Density-Lipoprotein (LDL) Uptake into Cells.

Loregger A, Nelson JK, Zelcer N. Loregger A, et al. Methods Mol Biol. 2017;1583:53-63. doi: 10.1007/978-1-4939-6875-6_5. Methods Mol Biol. 2017. PMID: 28205166

10

Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer.

Alioui A, Dufour J, Leoni V, Loregger A, Moeton M, Iuliano L, Zerbinati C, Septier A, Val P, Fouache A, Russo V, Volle DH, Lobaccaro JA, Zelcer N, Baron S. Alioui A, et al. Among authors: loregger a. Nat Commun. 2017 Sep 5;8(1):445. doi: 10.1038/s41467-017-00508-5. Nat Commun. 2017. Retraction in: Nat Commun. 2018 Jul 04;9(1):2660. doi: 10.1038/s41467-018-04653-3 PMID: 28874658 Free PMC article. Retracted.

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