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Inhibition of 3-phosphoglycerate dehydrogenase (PHGDH) by indole amides abrogates de novo serine synthesis in cancer cells.
Bioorg Med Chem Lett. 2019 Sep 1;29(17):2503-2510. doi: 10.1016/j.bmcl.2019.07.011. Epub 2019 Jul 6.
Bioorg Med Chem Lett. 2019.
PMID: 31327531
Free PMC article.
α-Ketothioamide Derivatives: A Promising Tool to Interrogate Phosphoglycerate Dehydrogenase (PHGDH).
Ravez S, Corbet C, Spillier Q, Dutu A, Robin AD, Mullarky E, Cantley LC, Feron O, Frédérick R.
Ravez S, et al. Among authors: robin ad.
J Med Chem. 2017 Feb 23;60(4):1591-1597. doi: 10.1021/acs.jmedchem.6b01166. Epub 2017 Jan 27.
J Med Chem. 2017.
PMID: 28085281
Free PMC article.
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