Wang HY - Search Results

1

Dynamic Changes in Gene Mutational Landscape With Preservation of Core Mutations in Mantle Cell Lymphoma Cells.

Zhang Q, Wang HY, Liu X, Roth MH, Shestov AA, Lee SC, Jain K, Soderquist C, Xiong QB, Ruella M, Strauser H, Glickson JD, Schuster SJ, Ptasznik A, Wasik MA. Zhang Q, et al. Among authors: wang hy. Front Oncol. 2019 Jul 3;9:568. doi: 10.3389/fonc.2019.00568. eCollection 2019. Front Oncol. 2019. PMID: 31334109 Free PMC article.

2

STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.

Zhang Q, Wang HY, Marzec M, Raghunath PN, Nagasawa T, Wasik MA. Zhang Q, et al. Among authors: wang hy. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6948-53. doi: 10.1073/pnas.0501959102. Epub 2005 May 3. Proc Natl Acad Sci U S A. 2005. PMID: 15870198 Free PMC article.

3

STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes.

Zhang Q, Wang HY, Woetmann A, Raghunath PN, Odum N, Wasik MA. Zhang Q, et al. Among authors: wang hy. Blood. 2006 Aug 1;108(3):1058-64. doi: 10.1182/blood-2005-08-007377. Blood. 2006. PMID: 16861352 Free PMC article.

4

STAT5A is epigenetically silenced by the tyrosine kinase NPM1-ALK and acts as a tumor suppressor by reciprocally inhibiting NPM1-ALK expression.

Zhang Q, Wang HY, Liu X, Wasik MA. Zhang Q, et al. Among authors: wang hy. Nat Med. 2007 Nov;13(11):1341-8. doi: 10.1038/nm1659. Epub 2007 Oct 7. Nat Med. 2007. PMID: 17922009

5

Lack of TNFalpha expression protects anaplastic lymphoma kinase-positive T-cell lymphoma (ALK+ TCL) cells from apoptosis.

Zhang Q, Wang HY, Bhutani G, Liu X, Paessler M, Tobias JW, Baldwin D, Swaminathan K, Milone MC, Wasik MA. Zhang Q, et al. Among authors: wang hy. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15843-8. doi: 10.1073/pnas.0907070106. Epub 2009 Aug 26. Proc Natl Acad Sci U S A. 2009. PMID: 19717436 Free PMC article.

6

Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming.

Marzec M, Halasa K, Liu X, Wang HY, Cheng M, Baldwin D, Tobias JW, Schuster SJ, Woetmann A, Zhang Q, Turner SD, Ødum N, Wasik MA. Marzec M, et al. Among authors: wang hy. J Immunol. 2013 Dec 15;191(12):6200-7. doi: 10.4049/jimmunol.1300744. Epub 2013 Nov 11. J Immunol. 2013. PMID: 24218456 Free PMC article.

7

Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells.

Lee SC, Shestov AA, Guo L, Zhang Q, Roman JC, Liu X, Wang HY, Pickup S, Nath K, Lu P, Hofbauer S, Mesaros C, Wang YL, Nelson DS, Schuster SJ, Blair IA, Glickson JD, Wasik MA. Lee SC, et al. Among authors: wang hy, wang yl. Mol Cancer Res. 2019 Jun;17(6):1365-1377. doi: 10.1158/1541-7786.MCR-18-0256. Epub 2019 Mar 12. Mol Cancer Res. 2019. PMID: 30862686 Free PMC article.

8

ACLY is the novel signaling target of PIP₂/PIP₃ and Lyn in acute myeloid leukemia.

Basappa J, Citir M, Zhang Q, Wang HY, Liu X, Melnikov O, Yahya H, Stein F, Muller R, Traynor-Kaplan A, Schultz C, Wasik MA, Ptasznik A. Basappa J, et al. Among authors: wang hy. Heliyon. 2020 May 7;6(5):e03910. doi: 10.1016/j.heliyon.2020.e03910. eCollection 2020 May. Heliyon. 2020. PMID: 32420483 Free PMC article.

9

Transdifferentiation of lymphoma into sarcoma associated with profound reprogramming of the epigenome.

Zhang Q, Orlando EJ, Wang HY, Bogusz AM, Liu X, Lacey SF, Strauser HT, Nunez-Cruz S, Nejati R, Zhang P, Brooks S, Watt C, Melenhorst JJ, June CH, Schuster SJ, Wasik MA. Zhang Q, et al. Among authors: wang hy. Blood. 2020 Oct 22;136(17):1980-1983. doi: 10.1182/blood.2020005123. Blood. 2020. PMID: 32518951 Free PMC article. No abstract available.

10

NPM-ALK-Induced Reprogramming of Mature TCR-Stimulated T Cells Results in Dedifferentiation and Malignant Transformation.

Pawlicki JM, Cookmeyer DL, Maseda D, Everett JK, Wei F, Kong H, Zhang Q, Wang HY, Tobias JW, Walter DM, Zullo KM, Javaid S, Watkins A, Wasik MA, Bushman FD, Riley JL. Pawlicki JM, et al. Among authors: wang hy. Cancer Res. 2021 Jun 15;81(12):3241-3254. doi: 10.1158/0008-5472.CAN-20-2297. Epub 2021 Feb 22. Cancer Res. 2021. PMID: 33619116 Free PMC article.

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