Manders F - Search Results

1

Characterizing Mutational Load and Clonal Composition of Human Blood.

Huber AR, Manders F, Oka R, van Boxtel R. Huber AR, et al. Among authors: manders f. J Vis Exp. 2019 Jul 11;(149). doi: 10.3791/59846. J Vis Exp. 2019. PMID: 31355782

2

Mutational signature in colorectal cancer caused by genotoxic pks⁺ E. coli.

Pleguezuelos-Manzano C, Puschhof J, Rosendahl Huber A, van Hoeck A, Wood HM, Nomburg J, Gurjao C, Manders F, Dalmasso G, Stege PB, Paganelli FL, Geurts MH, Beumer J, Mizutani T, Miao Y, van der Linden R, van der Elst S; Genomics England Research Consortium; Garcia KC, Top J, Willems RJL, Giannakis M, Bonnet R, Quirke P, Meyerson M, Cuppen E, van Boxtel R, Clevers H. Pleguezuelos-Manzano C, et al. Among authors: manders f. Nature. 2020 Apr;580(7802):269-273. doi: 10.1038/s41586-020-2080-8. Epub 2020 Feb 27. Nature. 2020. PMID: 32106218 Free PMC article.

3

Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis.

Hasaart KAL, Manders F, van der Hoorn ML, Verheul M, Poplonski T, Kuijk E, de Sousa Lopes SMC, van Boxtel R. Hasaart KAL, et al. Among authors: manders f. Sci Rep. 2020 Jul 31;10(1):12991. doi: 10.1038/s41598-020-69822-1. Sci Rep. 2020. PMID: 32737409 Free PMC article.

4

Increased risk of leukaemia in children with Down syndrome: a somatic evolutionary view.

Hasaart KAL, Bertrums EJM, Manders F, Goemans BF, van Boxtel R. Hasaart KAL, et al. Among authors: manders f. Expert Rev Mol Med. 2021 Apr 27;23:e5. doi: 10.1017/erm.2021.6. Expert Rev Mol Med. 2021. PMID: 33902785 Free PMC article.

5

[No title available]

[No authors listed] [No authors listed] PMID: 34233274

6

Antiviral treatment causes a unique mutational signature in cancers of transplantation recipients.

de Kanter JK, Peci F, Bertrums E, Rosendahl Huber A, van Leeuwen A, van Roosmalen MJ, Manders F, Verheul M, Oka R, Brandsma AM, Bierings M, Belderbos M, van Boxtel R. de Kanter JK, et al. Among authors: manders f. Cell Stem Cell. 2021 Oct 7;28(10):1726-1739.e6. doi: 10.1016/j.stem.2021.07.012. Epub 2021 Sep 7. Cell Stem Cell. 2021. PMID: 34496298 Free PMC article.

7

Mutation signatures of pediatric acute myeloid leukemia and normal blood progenitors associated with differential patient outcomes.

Brandsma AM, Bertrums EJM, van Roosmalen MJ, Hofman DA, Oka R, Verheul M, Manders F, Ubels J, Belderbos ME, van Boxtel R. Brandsma AM, et al. Among authors: manders f. Blood Cancer Discov. 2021 Sep;2(5):484-499. doi: 10.1158/2643-3230.BCD-21-0010. Blood Cancer Discov. 2021. PMID: 34642666 Free PMC article.

8

Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo.

Hasaart KAL, Manders F, Ubels J, Verheul M, van Roosmalen MJ, Groenen NM, Oka R, Kuijk E, Lopes SMCS, Boxtel RV. Hasaart KAL, et al. Among authors: manders f. iScience. 2022 Jan 6;25(2):103736. doi: 10.1016/j.isci.2022.103736. eCollection 2022 Feb 18. iScience. 2022. PMID: 35118356 Free PMC article.

9

MutationalPatterns: the one stop shop for the analysis of mutational processes.

Manders F, Brandsma AM, de Kanter J, Verheul M, Oka R, van Roosmalen MJ, van der Roest B, van Hoeck A, Cuppen E, van Boxtel R. Manders F, et al. BMC Genomics. 2022 Feb 15;23(1):134. doi: 10.1186/s12864-022-08357-3. BMC Genomics. 2022. PMID: 35168570 Free PMC article.

10

The Dynamics of Somatic Mutagenesis During Life in Humans.

Manders F, van Boxtel R, Middelkamp S. Manders F, et al. Front Aging. 2021 Dec 17;2:802407. doi: 10.3389/fragi.2021.802407. eCollection 2021. Front Aging. 2021. PMID: 35822044 Free PMC article. Review.

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