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Page 1
Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aβ Phagocytosis.
Miles LA, Hermans SJ, Crespi GAN, Gooi JH, Doughty L, Nero TL, Markulić J, Ebneth A, Wroblowski B, Oehlrich D, Trabanco AA, Rives ML, Royaux I, Hancock NC, Parker MW. Miles LA, et al. Among authors: parker mw. iScience. 2019 Sep 27;19:110-118. doi: 10.1016/j.isci.2019.07.023. Epub 2019 Jul 19. iScience. 2019. PMID: 31369984 Free PMC article.
Elucidation of the substrate binding site of Siah ubiquitin ligase.
House CM, Hancock NC, Möller A, Cromer BA, Fedorov V, Bowtell DD, Parker MW, Polekhina G. House CM, et al. Among authors: parker mw. Structure. 2006 Apr;14(4):695-701. doi: 10.1016/j.str.2005.12.013. Structure. 2006. PMID: 16615911 Free article.
Copper binding to the Alzheimer's disease amyloid precursor protein.
Kong GK, Miles LA, Crespi GA, Morton CJ, Ng HL, Barnham KJ, McKinstry WJ, Cappai R, Parker MW. Kong GK, et al. Among authors: parker mw. Eur Biophys J. 2008 Mar;37(3):269-79. doi: 10.1007/s00249-007-0234-3. Epub 2007 Nov 21. Eur Biophys J. 2008. PMID: 18030462 Free PMC article. Review.
Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Abeta peptides associated with Alzheimer's disease.
Wun KS, Miles LA, Crespi GA, Wycherley K, Ascher DB, Barnham KJ, Cappai R, Beyreuther K, Masters CL, Parker MW, McKinstry WJ. Wun KS, et al. Among authors: parker mw. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 May 1;64(Pt 5):438-41. doi: 10.1107/S1744309108011718. Epub 2008 Apr 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18453721 Free PMC article.
The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants.
Parker LJ, Ciccone S, Italiano LC, Primavera A, Oakley AJ, Morton CJ, Hancock NC, Bello ML, Parker MW. Parker LJ, et al. Among authors: parker mw. J Mol Biol. 2008 Jun 27;380(1):131-44. doi: 10.1016/j.jmb.2008.04.066. Epub 2008 May 4. J Mol Biol. 2008. PMID: 18511072 Free article.
Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation.
Parker LJ, Italiano LC, Morton CJ, Hancock NC, Ascher DB, Aitken JB, Harris HH, Campomanes P, Rothlisberger U, De Luca A, Lo Bello M, Ang WH, Dyson PJ, Parker MW. Parker LJ, et al. Among authors: parker mw. Chemistry. 2011 Jul 4;17(28):7806-16. doi: 10.1002/chem.201100586. Epub 2011 Jun 16. Chemistry. 2011. PMID: 21681839
488 results