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Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia.
McKenzie MD, Ghisi M, Oxley EP, Ngo S, Cimmino L, Esnault C, Liu R, Salmon JM, Bell CC, Ahmed N, Erlichster M, Witkowski MT, Liu GJ, Chopin M, Dakic A, Simankowicz E, Pomilio G, Vu T, Krsmanovic P, Su S, Tian L, Baldwin TM, Zalcenstein DA, DiRago L, Wang S, Metcalf D, Johnstone RW, Croker BA, Lancaster GI, Murphy AJ, Naik SH, Nutt SL, Pospisil V, Schroeder T, Wall M, Dawson MA, Wei AH, de Thé H, Ritchie ME, Zuber J, Dickins RA. McKenzie MD, et al. Among authors: ahmed n. Cell Stem Cell. 2019 Aug 1;25(2):258-272.e9. doi: 10.1016/j.stem.2019.07.001. Cell Stem Cell. 2019. PMID: 31374198 Free article.
Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios.
Hoppe PS, Schwarzfischer M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Moritz N, Endele M, Filipczyk A, Gambardella A, Ahmed N, Etzrodt M, Coutu DL, Rieger MA, Marr C, Strasser MK, Schauberger B, Burtscher I, Ermakova O, Bürger A, Lickert H, Nerlov C, Theis FJ, Schroeder T. Hoppe PS, et al. Among authors: ahmed n. Nature. 2016 Jul 14;535(7611):299-302. doi: 10.1038/nature18320. Nature. 2016. PMID: 27411635
Inflammatory signals directly instruct PU.1 in HSCs via TNF.
Etzrodt M, Ahmed N, Hoppe PS, Loeffler D, Skylaki S, Hilsenbeck O, Kokkaliaris KD, Kaltenbach HM, Stelling J, Nerlov C, Schroeder T. Etzrodt M, et al. Among authors: ahmed n. Blood. 2019 Feb 21;133(8):816-819. doi: 10.1182/blood-2018-02-832998. Epub 2018 Oct 9. Blood. 2019. PMID: 30301719 Free article.
PU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stress.
Chavez JS, Rabe JL, Loeffler D, Higa KC, Hernandez G, Mills TS, Ahmed N, Gessner RL, Ke Z, Idler BM, Niño KE, Kim H, Myers JR, Stevens BM, Davizon-Castillo P, Jordan CT, Nakajima H, Ashton J, Welner RS, Schroeder T, DeGregori J, Pietras EM. Chavez JS, et al. Among authors: ahmed n. J Exp Med. 2021 Jun 7;218(6):e20201169. doi: 10.1084/jem.20201169. J Exp Med. 2021. PMID: 33857288 Free PMC article.
Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1.
Tyrkalska SD, Pérez-Oliva AB, Rodríguez-Ruiz L, Martínez-Morcillo FJ, Alcaraz-Pérez F, Martínez-Navarro FJ, Lachaud C, Ahmed N, Schroeder T, Pardo-Sánchez I, Candel S, López-Muñoz A, Choudhuri A, Rossmann MP, Zon LI, Cayuela ML, García-Moreno D, Mulero V. Tyrkalska SD, et al. Among authors: ahmed n. Immunity. 2019 Jul 16;51(1):50-63.e5. doi: 10.1016/j.immuni.2019.05.005. Epub 2019 Jun 4. Immunity. 2019. PMID: 31174991 Free PMC article.
E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates.
Wanet A, Bassal MA, Patel SB, Marchi F, Mariani SA, Ahmed N, Zhang H, Borchiellini M, Chen S, Zhang J, Di Ruscio A, Miyake K, Tsai M, Paranjape A, Park SY, Karasuyama H, Schroeder T, Dzierzak E, Galli SJ, Tenen DG, Welner RS. Wanet A, et al. Among authors: ahmed n. Sci Immunol. 2021 Feb 5;6(56):eaba0178. doi: 10.1126/sciimmunol.aba0178. Sci Immunol. 2021. PMID: 33547048 Free PMC article.
4,181 results