Friedman SL - Search Results

1

Publisher Correction: SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis.

Athwal VS, Pritchett J, Martin K, Llewellyn J, Scott J, Harvey E, Zaitoun AM, Mullan AF, Zeef LAH, Friedman SL, Irving WL, Hanley NA, Guha IN, Piper Hanley K. Athwal VS, et al. Among authors: friedman sl. Sci Rep. 2019 Aug 6;9(1):11547. doi: 10.1038/s41598-019-47715-2. Sci Rep. 2019. PMID: 31383909 Free PMC article.

2

PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis.

Martin K, Pritchett J, Llewellyn J, Mullan AF, Athwal VS, Dobie R, Harvey E, Zeef L, Farrow S, Streuli C, Henderson NC, Friedman SL, Hanley NA, Piper Hanley K. Martin K, et al. Among authors: friedman sl. Nat Commun. 2016 Aug 18;7:12502. doi: 10.1038/ncomms12502. Nat Commun. 2016. PMID: 27535340 Free PMC article.

3

The XBP1 Arm of the Unfolded Protein Response Induces Fibrogenic Activity in Hepatic Stellate Cells Through Autophagy.

Kim RS, Hasegawa D, Goossens N, Tsuchida T, Athwal V, Sun X, Robinson CL, Bhattacharya D, Chou HI, Zhang DY, Fuchs BC, Lee Y, Hoshida Y, Friedman SL. Kim RS, et al. Among authors: friedman sl. Sci Rep. 2016 Dec 20;6:39342. doi: 10.1038/srep39342. Sci Rep. 2016. PMID: 27996033 Free PMC article.

4

SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis.

Athwal VS, Pritchett J, Llewellyn J, Martin K, Camacho E, Raza SM, Phythian-Adams A, Birchall LJ, Mullan AF, Su K, Pearmain L, Dolman G, Zaitoun AM, Friedman SL, MacDonald A, Irving WL, Guha IN, Hanley NA, Piper Hanley K. Athwal VS, et al. Among authors: friedman sl. EMBO Mol Med. 2017 Dec;9(12):1696-1710. doi: 10.15252/emmm.201707860. EMBO Mol Med. 2017. PMID: 29109128 Free PMC article.

5

SOX9 regulated matrix proteins are increased in patients serum and correlate with severity of liver fibrosis.

Athwal VS, Pritchett J, Martin K, Llewellyn J, Scott J, Harvey E, Zaitoun AM, Mullan AF, Zeef LAH, Friedman SL, Irving WL, Hanley NA, Guha IN, Piper Hanley K. Athwal VS, et al. Among authors: friedman sl. Sci Rep. 2018 Dec 17;8(1):17905. doi: 10.1038/s41598-018-36037-4. Sci Rep. 2018. PMID: 30559459 Free PMC article.

6

Pathogenesis of liver fibrosis.

Hernandez-Gea V, Friedman SL. Hernandez-Gea V, et al. Among authors: friedman sl. Annu Rev Pathol. 2011;6:425-56. doi: 10.1146/annurev-pathol-011110-130246. Annu Rev Pathol. 2011. PMID: 21073339 Review.

7

Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells.

Hicks DF, Goossens N, Blas-García A, Tsuchida T, Wooden B, Wallace MC, Nieto N, Lade A, Redhead B, Cederbaum AI, Dudley JT, Fuchs BC, Lee YA, Hoshida Y, Friedman SL. Hicks DF, et al. Among authors: friedman sl. Sci Rep. 2017 Mar 3;7:42563. doi: 10.1038/srep42563. Sci Rep. 2017. PMID: 28256512 Free PMC article.

8

Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury.

Sydor S, Manka P, Best J, Jafoui S, Sowa JP, Zoubek ME, Hernandez-Gea V, Cubero FJ, Kälsch J, Vetter D, Fiel MI, Hoshida Y, Bian CB, Nelson LJ, Moshage H, Faber KN, Paul A, Baba HA, Gerken G, Friedman SL, Canbay A, Bechmann LP. Sydor S, et al. Among authors: friedman sl. Sci Rep. 2017 Aug 14;7(1):8119. doi: 10.1038/s41598-017-08680-w. Sci Rep. 2017. PMID: 28808340 Free PMC article.

9

Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis.

Bhattacharya D, Becker C, Readhead B, Goossens N, Novik J, Fiel MI, Cousens LP, Magnusson B, Backmark A, Hicks R, Dudley JT, Friedman SL. Bhattacharya D, et al. Among authors: friedman sl. Sci Rep. 2021 Oct 21;11(1):20827. doi: 10.1038/s41598-021-99008-2. Sci Rep. 2021. PMID: 34675338 Free PMC article.

10

FASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models.

O'Farrell M, Duke G, Crowley R, Buckley D, Martins EB, Bhattacharya D, Friedman SL, Kemble G. O'Farrell M, et al. Among authors: friedman sl. Sci Rep. 2022 Sep 19;12(1):15661. doi: 10.1038/s41598-022-19459-z. Sci Rep. 2022. PMID: 36123383 Free PMC article.

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