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An RNA-centric dissection of host complexes controlling flavivirus infection.
Ooi YS, Majzoub K, Flynn RA, Mata MA, Diep J, Li JK, van Buuren N, Rumachik N, Johnson AG, Puschnik AS, Marceau CD, Mlera L, Grabowski JM, Kirkegaard K, Bloom ME, Sarnow P, Bertozzi CR, Carette JE. Ooi YS, et al. Among authors: flynn ra. Nat Microbiol. 2019 Dec;4(12):2369-2382. doi: 10.1038/s41564-019-0518-2. Epub 2019 Aug 5. Nat Microbiol. 2019. PMID: 31384002 Free PMC article.
Dissecting noncoding and pathogen RNA-protein interactomes.
Flynn RA, Martin L, Spitale RC, Do BT, Sagan SM, Zarnegar B, Qu K, Khavari PA, Quake SR, Sarnow P, Chang HY. Flynn RA, et al. RNA. 2015 Jan;21(1):135-43. doi: 10.1261/rna.047803.114. Epub 2014 Nov 19. RNA. 2015. PMID: 25411354 Free PMC article.
Structural imprints in vivo decode RNA regulatory mechanisms.
Spitale RC, Flynn RA, Zhang QC, Crisalli P, Lee B, Jung JW, Kuchelmeister HY, Batista PJ, Torre EA, Kool ET, Chang HY. Spitale RC, et al. Among authors: flynn ra. Nature. 2015 Mar 26;519(7544):486-90. doi: 10.1038/nature14263. Epub 2015 Mar 18. Nature. 2015. PMID: 25799993 Free PMC article.
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis.
Shao Z, Flynn RA, Crowe JL, Zhu Y, Liang J, Jiang W, Aryan F, Aoude P, Bertozzi CR, Estes VM, Lee BJ, Bhagat G, Zha S, Calo E. Shao Z, et al. Among authors: flynn ra. Nature. 2020 Mar;579(7798):291-296. doi: 10.1038/s41586-020-2041-2. Epub 2020 Feb 26. Nature. 2020. PMID: 32103174 Free PMC article.
A memory of eS25 loss drives resistance phenotypes.
Johnson AG, Flynn RA, Lapointe CP, Ooi YS, Zhao ML, Richards CM, Qiao W, Yamada SB, Couthouis J, Gitler AD, Carette JE, Puglisi JD. Johnson AG, et al. Among authors: flynn ra. Nucleic Acids Res. 2020 Jul 27;48(13):7279-7297. doi: 10.1093/nar/gkaa444. Nucleic Acids Res. 2020. PMID: 32463448 Free PMC article.
Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection.
Flynn RA, Belk JA, Qi Y, Yasumoto Y, Schmitz CO, Mumbach MR, Limaye A, Wei J, Alfajaro MM, Parker KR, Chang HY, Horvath TL, Carette JE, Bertozzi C, Wilen CB, Satpathy AT. Flynn RA, et al. bioRxiv [Preprint]. 2020 Oct 6:2020.10.06.327445. doi: 10.1101/2020.10.06.327445. bioRxiv. 2020. Update in: Cell. 2021 Apr 29;184(9):2394-2411.e16. doi: 10.1016/j.cell.2021.03.012 PMID: 33052334 Free PMC article. Updated. Preprint.
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.
Flynn RA, Belk JA, Qi Y, Yasumoto Y, Wei J, Alfajaro MM, Shi Q, Mumbach MR, Limaye A, DeWeirdt PC, Schmitz CO, Parker KR, Woo E, Chang HY, Horvath TL, Carette JE, Bertozzi CR, Wilen CB, Satpathy AT. Flynn RA, et al. Cell. 2021 Apr 29;184(9):2394-2411.e16. doi: 10.1016/j.cell.2021.03.012. Epub 2021 Mar 11. Cell. 2021. PMID: 33743211 Free PMC article.
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