Cortopassi WA - Search Results

1

Age- and stress-associated C. elegans granulins impair lysosomal function and induce a compensatory HLH-30/TFEB transcriptional response.

Butler VJ, Gao F, Corrales CI, Cortopassi WA, Caballero B, Vohra M, Ashrafi K, Cuervo AM, Jacobson MP, Coppola G, Kao AW. Butler VJ, et al. Among authors: cortopassi wa. PLoS Genet. 2019 Aug 9;15(8):e1008295. doi: 10.1371/journal.pgen.1008295. eCollection 2019 Aug. PLoS Genet. 2019. PMID: 31398187 Free PMC article.

2

Synthesis of the Ca²⁺-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signaling.

Lin WK, Bolton EL, Cortopassi WA, Wang Y, O'Brien F, Maciejewska M, Jacobson MP, Garnham C, Ruas M, Parrington J, Lei M, Sitsapesan R, Galione A, Terrar DA. Lin WK, et al. Among authors: cortopassi wa. J Biol Chem. 2017 Aug 11;292(32):13243-13257. doi: 10.1074/jbc.M117.789347. Epub 2017 May 24. J Biol Chem. 2017. PMID: 28539361 Free PMC article.

3

Structure-based Discovery of Novel CK2α-Binding Cyclic Peptides with Anti-cancer Activity.

Tang S, Zhang N, Zhou Y, Cortopassi WA, Jacobson MP, Zhao LJ, Zhong RG. Tang S, et al. Among authors: cortopassi wa. Mol Inform. 2019 Mar;38(3):e1800089. doi: 10.1002/minf.201800089. Epub 2018 Oct 11. Mol Inform. 2019. PMID: 30307134

4

Progranulin Stimulates the In Vitro Maturation of Pro-Cathepsin D at Acidic pH.

Butler VJ, Cortopassi WA, Argouarch AR, Ivry SL, Craik CS, Jacobson MP, Kao AW. Butler VJ, et al. Among authors: cortopassi wa. J Mol Biol. 2019 Mar 1;431(5):1038-1047. doi: 10.1016/j.jmb.2019.01.027. Epub 2019 Jan 25. J Mol Biol. 2019. PMID: 30690031 Free PMC article.

5

Structure-based identification of novel CK2 inhibitors with a linear 2-propenone scaffold as anti-cancer agents.

Qi X, Zhang N, Zhao L, Hu L, Cortopassi WA, Jacobson MP, Li X, Zhong R. Qi X, et al. Among authors: cortopassi wa. Biochem Biophys Res Commun. 2019 Apr 30;512(2):208-212. doi: 10.1016/j.bbrc.2019.03.016. Epub 2019 Mar 14. Biochem Biophys Res Commun. 2019. PMID: 30878184

6

Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH.

Charafeddine RA, Cortopassi WA, Lak P, Tan R, McKenney RJ, Jacobson MP, Barber DL, Wittmann T. Charafeddine RA, et al. Among authors: cortopassi wa. J Biol Chem. 2019 May 31;294(22):8779-8790. doi: 10.1074/jbc.RA118.007004. Epub 2019 Apr 16. J Biol Chem. 2019. PMID: 30992364 Free PMC article.

7

Multi-Granulin Domain Peptides Bind to Pro-Cathepsin D and Stimulate Its Enzymatic Activity More Effectively Than Progranulin in Vitro.

Butler VJ, Cortopassi WA, Gururaj S, Wang AL, Pierce OM, Jacobson MP, Kao AW. Butler VJ, et al. Among authors: cortopassi wa. Biochemistry. 2019 Jun 11;58(23):2670-2674. doi: 10.1021/acs.biochem.9b00275. Epub 2019 May 24. Biochemistry. 2019. PMID: 31099551 Free PMC article.

8

ATP-Competitive Inhibitors Midostaurin and Avapritinib Have Distinct Resistance Profiles in Exon 17-Mutant KIT.

Apsel Winger B, Cortopassi WA, Garrido Ruiz D, Ding L, Jang K, Leyte-Vidal A, Zhang N, Esteve-Puig R, Jacobson MP, Shah NP. Apsel Winger B, et al. Among authors: cortopassi wa. Cancer Res. 2019 Aug 15;79(16):4283-4292. doi: 10.1158/0008-5472.CAN-18-3139. Epub 2019 Jul 3. Cancer Res. 2019. PMID: 31270078 Free PMC article.

9

Mutagenesis, Hydrogen-Deuterium Exchange, and Molecular Docking Investigations Establish the Dimeric Interface of Human Platelet-Type 12-Lipoxygenase.

Tsai WC, Aleem AM, Whittington C, Cortopassi WA, Kalyanaraman C, Baroz A, Iavarone AT, Skrzypczak-Jankun E, Jacobson MP, Offenbacher AR, Holman T. Tsai WC, et al. Among authors: cortopassi wa. Biochemistry. 2021 Mar 16;60(10):802-812. doi: 10.1021/acs.biochem.1c00053. Epub 2021 Feb 26. Biochemistry. 2021. PMID: 33635645

10

Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues.

Cortopassi WA, Gunderson E, Annunciato Y, Silva AES, Dos Santos Ferreira A, Garcia Teles CB, Pimentel AS, Ramamoorthi R, Gazarini ML, Meneghetti MR, Guido RVC, Pereira DB, Jacobson MP, Krettli AU, Caroline C Aguiar A. Cortopassi WA, et al. Int J Parasitol Drugs Drug Resist. 2022 Dec;20:121-128. doi: 10.1016/j.ijpddr.2022.10.003. Epub 2022 Oct 31. Int J Parasitol Drugs Drug Resist. 2022. PMID: 36375339 Free PMC article.

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