Ravn P - Search Results

1

Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition.

Kaneko K, Fu Y, Lin HY, Cordonier EL, Mo Q, Gao Y, Yao T, Naylor J, Howard V, Saito K, Xu P, Chen SS, Chen MH, Xu Y, Williams KW, Ravn P, Fukuda M. Kaneko K, et al. Among authors: ravn p. J Clin Invest. 2019 Aug 12;129(9):3786-3791. doi: 10.1172/JCI126107. eCollection 2019 Aug 12. J Clin Invest. 2019. PMID: 31403469 Free PMC article.

2

Gut Hormone GIP Induces Inflammation and Insulin Resistance in the Hypothalamus.

Fu Y, Kaneko K, Lin HY, Mo Q, Xu Y, Suganami T, Ravn P, Fukuda M. Fu Y, et al. Among authors: ravn p. Endocrinology. 2020 Sep 1;161(9):bqaa102. doi: 10.1210/endocr/bqaa102. Endocrinology. 2020. PMID: 32603429 Free PMC article.

3

Pharmacological antagonism of the incretin system protects against diet-induced obesity.

Svendsen B, Capozzi ME, Nui J, Hannou SA, Finan B, Naylor J, Ravn P, D'Alessio DA, Campbell JE. Svendsen B, et al. Among authors: ravn p. Mol Metab. 2020 Feb;32:44-55. doi: 10.1016/j.molmet.2019.11.018. Epub 2019 Dec 3. Mol Metab. 2020. PMID: 32029229 Free PMC article.

4

Use of CRISPR/Cas9-engineered INS-1 pancreatic β cells to define the pharmacology of dual GIPR/GLP-1R agonists.

Naylor J, Suckow AT, Seth A, Baker DJ, Sermadiras I, Ravn P, Howes R, Li J, Snaith MR, Coghlan MP, Hornigold DC. Naylor J, et al. Among authors: ravn p. Biochem J. 2016 Sep 15;473(18):2881-91. doi: 10.1042/BCJ20160476. Epub 2016 Jul 15. Biochem J. 2016. PMID: 27422784

5

Development and characterisation of a novel glucagon like peptide-1 receptor antibody.

Biggs EK, Liang L, Naylor J, Madalli S, Collier R, Coghlan MP, Baker DJ, Hornigold DC, Ravn P, Reimann F, Gribble FM. Biggs EK, et al. Among authors: ravn p. Diabetologia. 2018 Mar;61(3):711-721. doi: 10.1007/s00125-017-4491-0. Epub 2017 Nov 9. Diabetologia. 2018. PMID: 29119245 Free PMC article.

6

Structural and pharmacological characterization of novel potent and selective monoclonal antibody antagonists of glucose-dependent insulinotropic polypeptide receptor.

Ravn P, Madhurantakam C, Kunze S, Matthews E, Priest C, O'Brien S, Collinson A, Papworth M, Fritsch-Fredin M, Jermutus L, Benthem L, Gruetter M, Jackson RH. Ravn P, et al. J Biol Chem. 2013 Jul 5;288(27):19760-72. doi: 10.1074/jbc.M112.426288. Epub 2013 May 20. J Biol Chem. 2013. PMID: 23689510 Free PMC article.

7

Superior reductions in hepatic steatosis and fibrosis with co-administration of a glucagon-like peptide-1 receptor agonist and obeticholic acid in mice.

Jouihan H, Will S, Guionaud S, Boland ML, Oldham S, Ravn P, Celeste A, Trevaskis JL. Jouihan H, et al. Among authors: ravn p. Mol Metab. 2017 Nov;6(11):1360-1370. doi: 10.1016/j.molmet.2017.09.001. Epub 2017 Sep 14. Mol Metab. 2017. PMID: 29107284 Free PMC article.

8

Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells.

Gray SM, Xin Y, Ross EC, Chazotte BM, Capozzi ME, El K, Svendsen B, Ravn P, Sloop KW, Tong J, Gromada J, Campbell JE, D'Alessio DA. Gray SM, et al. Among authors: ravn p. J Biol Chem. 2020 Aug 14;295(33):11529-11541. doi: 10.1074/jbc.RA120.014368. Epub 2020 Jun 18. J Biol Chem. 2020. PMID: 32554468 Free PMC article.

9

Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery.

Larraufie P, Roberts GP, McGavigan AK, Kay RG, Li J, Leiter A, Melvin A, Biggs EK, Ravn P, Davy K, Hornigold DC, Yeo GSH, Hardwick RH, Reimann F, Gribble FM. Larraufie P, et al. Among authors: ravn p. Cell Rep. 2019 Feb 5;26(6):1399-1408.e6. doi: 10.1016/j.celrep.2019.01.047. Cell Rep. 2019. PMID: 30726726 Free PMC article. Clinical Trial.

10

Recombinant expression and in vitro characterisation of active Huwentoxin-IV.

Sermadiras I, Revell J, Linley JE, Sandercock A, Ravn P. Sermadiras I, et al. Among authors: ravn p. PLoS One. 2013 Dec 6;8(12):e83202. doi: 10.1371/journal.pone.0083202. eCollection 2013. PLoS One. 2013. PMID: 24324842 Free PMC article.

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