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Analysis of circulating cell-free DNA identifies KRAS copy number gain and mutation as a novel prognostic marker in Pancreatic cancer.
Mohan S, Ayub M, Rothwell DG, Gulati S, Kilerci B, Hollebecque A, Sun Leong H, Smith NK, Sahoo S, Descamps T, Zhou C, Hubner RA, McNamara MG, Lamarca A, Valle JW, Dive C, Brady G. Mohan S, et al. Among authors: brady g. Sci Rep. 2019 Aug 12;9(1):11610. doi: 10.1038/s41598-019-47489-7. Sci Rep. 2019. PMID: 31406261 Free PMC article.
In silico error correction improves cfDNA mutation calling.
Kim CS, Mohan S, Ayub M, Rothwell DG, Dive C, Brady G, Miller C. Kim CS, et al. Among authors: brady g. Bioinformatics. 2019 Jul 15;35(14):2380-2385. doi: 10.1093/bioinformatics/bty1004. Bioinformatics. 2019. PMID: 30520956 Free PMC article.
Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample.
Rothwell DG, Smith N, Morris D, Leong HS, Li Y, Hollebecque A, Ayub M, Carter L, Antonello J, Franklin L, Miller C, Blackhall F, Dive C, Brady G. Rothwell DG, et al. Among authors: brady g. Mol Oncol. 2016 Apr;10(4):566-74. doi: 10.1016/j.molonc.2015.11.006. Epub 2015 Nov 19. Mol Oncol. 2016. PMID: 26639657 Free PMC article.
Development of a circulating miRNA assay to monitor tumor burden: From mouse to man.
Greystoke A, Ayub M, Rothwell DG, Morris D, Burt D, Hodgkinson CL, Morrow CJ, Smith N, Aung K, Valle J, Carter L, Blackhall F, Dive C, Brady G. Greystoke A, et al. Among authors: brady g. Mol Oncol. 2016 Feb;10(2):282-91. doi: 10.1016/j.molonc.2015.10.004. Epub 2015 Oct 28. Mol Oncol. 2016. PMID: 26654130 Free PMC article.
Vasculogenic mimicry in small cell lung cancer.
Williamson SC, Metcalf RL, Trapani F, Mohan S, Antonello J, Abbott B, Leong HS, Chester CP, Simms N, Polanski R, Nonaka D, Priest L, Fusi A, Carlsson F, Carlsson A, Hendrix MJ, Seftor RE, Seftor EA, Rothwell DG, Hughes A, Hicks J, Miller C, Kuhn P, Brady G, Simpson KL, Blackhall FH, Dive C. Williamson SC, et al. Among authors: brady g. Nat Commun. 2016 Nov 9;7:13322. doi: 10.1038/ncomms13322. Nat Commun. 2016. PMID: 27827359 Free PMC article.
Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer.
Carter L, Rothwell DG, Mesquita B, Smowton C, Leong HS, Fernandez-Gutierrez F, Li Y, Burt DJ, Antonello J, Morrow CJ, Hodgkinson CL, Morris K, Priest L, Carter M, Miller C, Hughes A, Blackhall F, Dive C, Brady G. Carter L, et al. Among authors: brady g. Nat Med. 2017 Jan;23(1):114-119. doi: 10.1038/nm.4239. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869802
SnapShot: Circulating Tumor Cells.
Dive C, Brady G. Dive C, et al. Among authors: brady g. Cell. 2017 Feb 9;168(4):742-742.e1. doi: 10.1016/j.cell.2017.01.026. Cell. 2017. PMID: 28187292 Free article.
Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study.
Rothwell DG, Ayub M, Cook N, Thistlethwaite F, Carter L, Dean E, Smith N, Villa S, Dransfield J, Clipson A, White D, Nessa K, Ferdous S, Howell M, Gupta A, Kilerci B, Mohan S, Frese K, Gulati S, Miller C, Jordan A, Eaton H, Hickson N, O'Brien C, Graham D, Kelly C, Aruketty S, Metcalf R, Chiramel J, Tinsley N, Vickers AJ, Kurup R, Frost H, Stevenson J, Southam S, Landers D, Wallace A, Marais R, Hughes AM, Brady G, Dive C, Krebs MG. Rothwell DG, et al. Among authors: brady g. Nat Med. 2019 May;25(5):738-743. doi: 10.1038/s41591-019-0380-z. Epub 2019 Apr 22. Nat Med. 2019. PMID: 31011204 Free article.
275 results