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Page 1
A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite.
Albulescu LO, Kazandjian T, Slagboom J, Bruyneel B, Ainsworth S, Alsolaiss J, Wagstaff SC, Whiteley G, Harrison RA, Ulens C, Kool J, Casewell NR. Albulescu LO, et al. Among authors: alsolaiss j. Front Pharmacol. 2019 Jul 30;10:848. doi: 10.3389/fphar.2019.00848. eCollection 2019. Front Pharmacol. 2019. PMID: 31417406 Free PMC article.
Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro cross-reactivity and in vivo neutralisation of geographically diverse snake venoms.
Alomran N, Alsolaiss J, Albulescu LO, Crittenden E, Harrison RA, Ainsworth S, Casewell NR. Alomran N, et al. Among authors: alsolaiss j. PLoS Negl Trop Dis. 2021 Aug 18;15(8):e0009659. doi: 10.1371/journal.pntd.0009659. eCollection 2021 Aug. PLoS Negl Trop Dis. 2021. PMID: 34407084 Free PMC article.
Author Correction: A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite.
Albulescu LO, Xie C, Ainsworth S, Alsolaiss J, Crittenden E, Dawson CA, Softley R, Bartlett KE, Harrison RA, Kool J, Casewell NR. Albulescu LO, et al. Among authors: alsolaiss j. Nat Commun. 2021 Jun 24;12(1):4027. doi: 10.1038/s41467-021-24308-0. Nat Commun. 2021. PMID: 34168149 Free PMC article. No abstract available.
In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus.
Menzies SK, Clare RH, Xie C, Westhorpe A, Hall SR, Edge RJ, Alsolaiss J, Crittenden E, Marriott AE, Harrison RA, Kool J, Casewell NR. Menzies SK, et al. Among authors: alsolaiss j. Toxicon X. 2022 Mar 18;14:100118. doi: 10.1016/j.toxcx.2022.100118. eCollection 2022 Jun. Toxicon X. 2022. PMID: 35321116 Free PMC article.
Preclinical antivenom-efficacy testing reveals potentially disturbing deficiencies of snakebite treatment capability in East Africa.
Harrison RA, Oluoch GO, Ainsworth S, Alsolaiss J, Bolton F, Arias AS, Gutiérrez JM, Rowley P, Kalya S, Ozwara H, Casewell NR. Harrison RA, et al. Among authors: alsolaiss j. PLoS Negl Trop Dis. 2017 Oct 18;11(10):e0005969. doi: 10.1371/journal.pntd.0005969. eCollection 2017 Oct. PLoS Negl Trop Dis. 2017. PMID: 29045429 Free PMC article.
18 results