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Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease.
Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J, Bedi KC Jr, Margulies KB, Sanz-Moreno V, Hobbs A, Hodivala-Dilke K. Dukinfield M, et al. J Pathol. 2019 Dec;249(4):523-535. doi: 10.1002/path.5340. Epub 2019 Oct 30. J Pathol. 2019. PMID: 31424556 Free PMC article.
Integrins: the keys to unlocking angiogenesis.
Silva R, D'Amico G, Hodivala-Dilke KM, Reynolds LE. Silva R, et al. Arterioscler Thromb Vasc Biol. 2008 Oct;28(10):1703-13. doi: 10.1161/ATVBAHA.108.172015. Epub 2008 Jul 24. Arterioscler Thromb Vasc Biol. 2008. PMID: 18658045 Review.
ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning.
D'Amico G, Fernandez I, Gómez-Escudero J, Kim H, Maniati E, Azman MS, Mardakheh FK, Serrels B, Serrels A, Parsons M, Squire A, Birdsey GM, Randi AM, Bolado-Carrancio A, Gangeswaran R, Reynolds LE, Bodrug N, Wang Y, Wang J, Meier P, Hodivala-Dilke KM. D'Amico G, et al. Development. 2022 Jul 1;149(13):dev200528. doi: 10.1242/dev.200528. Epub 2022 Jul 12. Development. 2022. PMID: 35723257 Free PMC article.
Dual role of pericyte α6β1-integrin in tumour blood vessels.
Reynolds LE, D'Amico G, Lechertier T, Papachristodoulou A, Muñoz-Félix JM, De Arcangelis A, Baker M, Serrels B, Hodivala-Dilke KM. Reynolds LE, et al. J Cell Sci. 2017 May 1;130(9):1583-1595. doi: 10.1242/jcs.197848. Epub 2017 Mar 13. J Cell Sci. 2017. PMID: 28289267 Free PMC article.
Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction.
Li Z, Solomonidis EG, Meloni M, Taylor RS, Duffin R, Dobie R, Magalhaes MS, Henderson BEP, Louwe PA, D'Amico G, Hodivala-Dilke KM, Shah AM, Mills NL, Simons BD, Gray GA, Henderson NC, Baker AH, Brittan M. Li Z, et al. Eur Heart J. 2019 Aug 7;40(30):2507-2520. doi: 10.1093/eurheartj/ehz305. Eur Heart J. 2019. PMID: 31162546 Free PMC article.
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gómez-Escudero J, Muñoz-Félix JM, Batista S, Dukinfield M, Demircioglu F, Wong PP, Matchett KP, Henderson NC, D'Amico G, Parsons M, Harwood C, Meier P, Hodivala-Dilke KM. Lechertier T, et al. Nat Commun. 2020 Jun 4;11(1):2810. doi: 10.1038/s41467-020-16618-6. Nat Commun. 2020. PMID: 32499572 Free PMC article.
Regulation of lymphatic-blood vessel separation by endothelial Rac1.
D'Amico G, Jones DT, Nye E, Sapienza K, Ramjuan AR, Reynolds LE, Robinson SD, Kostourou V, Martinez D, Aubyn D, Grose R, Thomas GJ, Spencer-Dene B, Zicha D, Davies D, Tybulewicz V, Hodivala-Dilke KM. D'Amico G, et al. Development. 2009 Dec;136(23):4043-53. doi: 10.1242/dev.035014. Development. 2009. PMID: 19906871 Free PMC article.
844 results