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Synthesis, Identification, and Structure-Activity Relationship Analysis of GATA4 and NKX2-5 Protein-Protein Interaction Modulators.
Jumppanen M, Kinnunen SM, Välimäki MJ, Talman V, Auno S, Bruun T, Boije Af Gennäs G, Xhaard H, Aumüller IB, Ruskoaho H, Yli-Kauhaluoma J. Jumppanen M, et al. Among authors: talman v. J Med Chem. 2019 Sep 12;62(17):8284-8310. doi: 10.1021/acs.jmedchem.9b01086. Epub 2019 Sep 3. J Med Chem. 2019. PMID: 31431011 Free PMC article.
Scaffold hopping from (5-hydroxymethyl) isophthalates to multisubstituted pyrimidines diminishes binding affinity to the C1 domain of protein kinase C.
Provenzani R, Tarvainen I, Brandoli G, Lempinen A, Artes S, Turku A, Jäntti MH, Talman V, Yli-Kauhaluoma J, Tuominen RK, Boije Af Gennäs G. Provenzani R, et al. Among authors: talman v. PLoS One. 2018 Apr 11;13(4):e0195668. doi: 10.1371/journal.pone.0195668. eCollection 2018. PLoS One. 2018. PMID: 29641588 Free PMC article.
34 results