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Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B.
Vögtle T, Sharma S, Mori J, Nagy Z, Semeniak D, Scandola C, Geer MJ, Smith CW, Lane J, Pollack S, Lassila R, Jouppila A, Barr AJ, Ogg DJ, Howard TD, McMiken HJ, Warwicker J, Geh C, Rowlinson R, Abbott WM, Eckly A, Schulze H, Wright GJ, Mazharian A, Fütterer K, Rajesh S, Douglas MR, Senis YA. Vögtle T, et al. Among authors: eckly a. Elife. 2019 Aug 22;8:e46840. doi: 10.7554/eLife.46840. Elife. 2019. PMID: 31436532 Free PMC article.
Use of electron microscopy to study megakaryocytes.
Scandola C, Erhardt M, Rinckel JY, Proamer F, Gachet C, Eckly A. Scandola C, et al. Among authors: eckly a. Platelets. 2020 Jul 3;31(5):589-598. doi: 10.1080/09537104.2019.1708885. Epub 2020 Jan 5. Platelets. 2020. PMID: 31903825 Free article. Review.
Megakaryocytes use in vivo podosome-like structures working collectively to penetrate the endothelial barrier of bone marrow sinusoids.
Eckly A, Scandola C, Oprescu A, Michel D, Rinckel JY, Proamer F, Hoffmann D, Receveur N, Léon C, Bear JE, Ghalloussi D, Harousseau G, Bergmeier W, Lanza F, Gaits-Iacovoni F, de la Salle H, Gachet C. Eckly A, et al. J Thromb Haemost. 2020 Nov;18(11):2987-3001. doi: 10.1111/jth.15024. Epub 2020 Aug 25. J Thromb Haemost. 2020. PMID: 32702204 Free article.
Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion.
Léon C, Eckly A, Hechler B, Aleil B, Freund M, Ravanat C, Jourdain M, Nonne C, Weber J, Tiedt R, Gratacap MP, Severin S, Cazenave JP, Lanza F, Skoda R, Gachet C. Léon C, et al. Among authors: eckly a. Blood. 2007 Nov 1;110(9):3183-91. doi: 10.1182/blood-2007-03-080184. Epub 2007 Jul 30. Blood. 2007. PMID: 17664350 Free article.
97 results