Barrat FJ - Search Results

1

Role of type I interferons and innate immunity in systemic sclerosis: unbalanced activities on distinct cell types?

Barrat FJ, Lu TT. Barrat FJ, et al. Curr Opin Rheumatol. 2019 Nov;31(6):569-575. doi: 10.1097/BOR.0000000000000659. Curr Opin Rheumatol. 2019. PMID: 31436583 Free PMC article. Review.

2

Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8.

Ah Kioon MD, Tripodo C, Fernandez D, Kirou KA, Spiera RF, Crow MK, Gordon JK, Barrat FJ. Ah Kioon MD, et al. Among authors: barrat fj. Sci Transl Med. 2018 Jan 10;10(423):eaam8458. doi: 10.1126/scitranslmed.aam8458. Sci Transl Med. 2018. PMID: 29321259 Free PMC article.

3

A pathogenic role of plasmacytoid dendritic cells in autoimmunity and chronic viral infection.

Barrat FJ, Su L. Barrat FJ, et al. J Exp Med. 2019 Sep 2;216(9):1974-1985. doi: 10.1084/jem.20181359. Epub 2019 Aug 16. J Exp Med. 2019. PMID: 31420375 Free PMC article. Review.

4

Noncytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells In Vitro and Suppresses Cutaneous Inflammation in the Mouse.

Ah Kioon MD, Pierides M, Pannellini T, Lin G, Nathan CF, Barrat FJ. Ah Kioon MD, et al. Among authors: barrat fj. J Immunol. 2021 Apr 1;206(7):1631-1641. doi: 10.4049/jimmunol.2000951. Epub 2021 Mar 5. J Immunol. 2021. PMID: 33674446 Free PMC article.

5

Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responses.

Chaudhary V, Ah Kioon MD, Hwang SM, Mishra B, Lakin K, Kirou KA, Zhang-Sun J, Wiseman RL, Spiera RF, Crow MK, Gordon JK, Cubillos-Ruiz JR, Barrat FJ. Chaudhary V, et al. Among authors: barrat fj. J Exp Med. 2022 Nov 7;219(11):e20221085. doi: 10.1084/jem.20221085. Epub 2022 Sep 2. J Exp Med. 2022. PMID: 36053251 Free PMC article.

6

Altered X-chromosome inactivation of the TLR7/8 locus and heterogeneity of pDCs in systemic sclerosis.

Du Y, Faz-Lopez B, Ah Kioon MD, Cenac C, Pierides M, Lakin KS, Spiera RF, Chaumeil J, Truchetet ME, Gordon JK, Guéry JC, Barrat FJ. Du Y, et al. Among authors: barrat fj. J Exp Med. 2025 Mar 3;222(3):e20231809. doi: 10.1084/jem.20231809. Epub 2024 Dec 13. J Exp Med. 2025. PMID: 39670995

7

Mechanosensing regulates pDC activation in the skin through NRF2 activation.

Chaudhary V, Mishra B, Ah Kioon MD, Du Y, Ivashkiv LB, Crow MK, Barrat FJ. Chaudhary V, et al. Among authors: barrat fj. J Exp Med. 2025 Mar 3;222(3):e20240852. doi: 10.1084/jem.20240852. Epub 2024 Dec 13. J Exp Med. 2025. PMID: 39670996

8

Importance of Nucleic Acid Recognition in Inflammation and Autoimmunity.

Barrat FJ, Elkon KB, Fitzgerald KA. Barrat FJ, et al. Annu Rev Med. 2016;67:323-36. doi: 10.1146/annurev-med-052814-023338. Epub 2015 Nov 2. Annu Rev Med. 2016. PMID: 26526766 Review.

9

Interferon target-gene expression and epigenomic signatures in health and disease.

Barrat FJ, Crow MK, Ivashkiv LB. Barrat FJ, et al. Nat Immunol. 2019 Dec;20(12):1574-1583. doi: 10.1038/s41590-019-0466-2. Epub 2019 Nov 19. Nat Immunol. 2019. PMID: 31745335 Free PMC article. Review.

10

Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation.

Du Y, Ah Kioon MD, Laurent P, Chaudhary V, Pierides M, Yang C, Oliver D, Ivashkiv LB, Barrat FJ. Du Y, et al. Among authors: barrat fj. J Exp Med. 2022 Jul 4;219(7):e20212142. doi: 10.1084/jem.20212142. Epub 2022 May 31. J Exp Med. 2022. PMID: 35640018 Free PMC article.

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