Collen D - Search Results

1

Characterization of a chimeric plasminogen activator consisting of amino acids 1 to 274 of tissue-type plasminogen activator and amino acids 138 to 411 of single-chain urokinase-type plasminogen activator.

Lijnen HR, Nelles L, Van Hoef B, Demarsin E, Collen D. Lijnen HR, et al. Among authors: collen d. J Biol Chem. 1988 Dec 15;263(35):19083-91. J Biol Chem. 1988. PMID: 3143723 Free article.

A chimeric plasminogen activator (t-PA/scu-PA-s), consisting of amino acids 1-263 of tissue-type plasminogen activator (t-PA) and 144-411 of single-chain urokinase-type plasminogen activator (scu-PA), was previously shown to maintain the enzymatic properties of scu-PA but to have …

A chimeric plasminogen activator (t-PA/scu-PA-s), consisting of amino acids 1-263 of tissue-type plasminogen activator (t-PA) and 144-411 of …

2

Biochemical and biological properties of a recombinant tissue-type plasminogen activator derived from the rat JMI-229 cell line.

Lijnen HR, Webb PD, Van Hoef B, De Cock F, Stassen JM, Prior SD, Collen D. Lijnen HR, et al. Among authors: collen d. Thromb Haemost. 1992 Feb 3;67(2):239-47. Thromb Haemost. 1992. PMID: 1621244

3

Biochemical, thrombolytic and pharmacokinetic properties of rt-PA P47G, K49N, a substitution variant of human tissue-type plasminogen activator.

Nelles L, Li XK, Vanlinthout I, De Cock F, Lijnen HR, Collen D. Nelles L, et al. Among authors: collen d. Thromb Haemost. 1992 Apr 2;67(4):445-52. Thromb Haemost. 1992. PMID: 1631793

4

K1K2Pu, a recombinant t-PA/u-PA chimera with increased thrombolytic potency, consisting of amino acids 1 to 3 and 87 to 274 of human tissue-type plasminogen activator (t-PA) and amino acids 138 to 411 of human single chain urokinase-type plasminogen activator (scu-PA). Purification in centigram quantities and conditioning for use in man.

Collen D, Nelles L, De Cock F, Lemmens G, Van Coetsem T, Demarsin E, Lijnen HR. Collen D, et al. Thromb Res. 1992 Feb 1;65(3):421-38. doi: 10.1016/0049-3848(92)90172-7. Thromb Res. 1992. PMID: 1631805

5

Interaction of AP-1-, AP-2-, and Sp1-like proteins with two distinct sites in the upstream regulatory region of the plasminogen activator inhibitor-1 gene mediates the phorbol 12-myristate 13-acetate response.

Descheemaeker KA, Wyns S, Nelles L, Auwerx J, Ny T, Collen D. Descheemaeker KA, et al. Among authors: collen d. J Biol Chem. 1992 Jul 25;267(21):15086-91. J Biol Chem. 1992. PMID: 1634545 Free article.

6

A monoclonal antibody specific for two-chain urokinase-type plasminogen activator. Application to the study of the mechanism of clot lysis with single-chain urokinase-type plasminogen activator in plasma.

Declerck PJ, Lijnen HR, Verstreken M, Moreau H, Collen D. Declerck PJ, et al. Among authors: collen d. Blood. 1990 May 1;75(9):1794-800. Blood. 1990. PMID: 1691934 Free article.

7

On the molecular interactions between plasminogen-staphylokinase, alpha 2-antiplasmin and fibrin.

Lijnen HR, Van Hoef B, Matsuo O, Collen D. Lijnen HR, et al. Among authors: collen d. Biochim Biophys Acta. 1992 Jan 9;1118(2):144-8. doi: 10.1016/0167-4838(92)90142-z. Biochim Biophys Acta. 1992. PMID: 1730031

8

Biochemical and biologic properties of rt-PA del (K296-G302), a recombinant human tissue-type plasminogen activator deletion mutant resistant to plasminogen activator inhibitor-1.

Li XK, Lijnen HR, Nelles L, Van Hoef B, Stassen JM, Collen D. Li XK, et al. Among authors: collen d. Blood. 1992 Jan 15;79(2):417-29. Blood. 1992. PMID: 1730087 Free article.

9

Enhancement of clot lysis in vitro and in vivo with a bispecific monoclonal antibody directed against human fibrin and against urokinase-type plasminogen activator.

Kurokawa T, Iwasa S, Kakinuma A, Stassen JM, Lijnen HR, Collen D. Kurokawa T, et al. Among authors: collen d. Thromb Haemost. 1991 Dec 2;66(6):684-93. Thromb Haemost. 1991. PMID: 1796414

10

Effect of chemical conjugation of recombinant single-chain urokinase-type plasminogen activator with monoclonal antiplatelet antibodies on platelet aggregation and on plasma clot lysis in vitro and in vivo.

Dewerchin M, Lijnen HR, Stassen JM, De Cock F, Quertermous T, Ginsberg MH, Plow EF, Collen D. Dewerchin M, et al. Among authors: collen d. Blood. 1991 Aug 15;78(4):1005-18. Blood. 1991. PMID: 1831057 Free article.

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