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Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7.
Jaeger K, Bruenle S, Weinert T, Guba W, Muehle J, Miyazaki T, Weber M, Furrer A, Haenggi N, Tetaz T, Huang CY, Mattle D, Vonach JM, Gast A, Kuglstatter A, Rudolph MG, Nogly P, Benz J, Dawson RJP, Standfuss J. Jaeger K, et al. Among authors: rudolph mg. Cell. 2019 Aug 22;178(5):1222-1230.e10. doi: 10.1016/j.cell.2019.07.028. Cell. 2019. PMID: 31442409 Free PMC article.
A Real-World Perspective on Molecular Design.
Kuhn B, Guba W, Hert J, Banner D, Bissantz C, Ceccarelli S, Haap W, Körner M, Kuglstatter A, Lerner C, Mattei P, Neidhart W, Pinard E, Rudolph MG, Schulz-Gasch T, Woltering T, Stahl M. Kuhn B, et al. Among authors: rudolph mg. J Med Chem. 2016 May 12;59(9):4087-102. doi: 10.1021/acs.jmedchem.5b01875. Epub 2016 Feb 24. J Med Chem. 2016. PMID: 26878596
Ligand channel in pharmacologically stabilized rhodopsin.
Mattle D, Kuhn B, Aebi J, Bedoucha M, Kekilli D, Grozinger N, Alker A, Rudolph MG, Schmid G, Schertler GFX, Hennig M, Standfuss J, Dawson RJP. Mattle D, et al. Among authors: rudolph mg. Proc Natl Acad Sci U S A. 2018 Apr 3;115(14):3640-3645. doi: 10.1073/pnas.1718084115. Epub 2018 Mar 19. Proc Natl Acad Sci U S A. 2018. PMID: 29555765 Free PMC article.
Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor.
Hunziker D, Reinehr S, Palmhof M, Wagner N, Biniasch T, Stute G, Mattei P, Schmitz P, DiGiorgio P, Hert J, Rudolph MG, Benz J, Stihle M, Gsell B, Müller S, Gasser R, Schonhoven N, Ullmer C, Joachim SC. Hunziker D, et al. Among authors: rudolph mg. Front Pharmacol. 2022 Jan 18;12:699535. doi: 10.3389/fphar.2021.699535. eCollection 2021. Front Pharmacol. 2022. PMID: 35126098 Free PMC article.
86 results