Highton AJ - Search Results

1

Single-cell transcriptome analysis of CD8 ⁺ T-cell memory inflation.

Highton AJ, Zinser ME, Lee LN, Hutchings CL, De Lara C, Phetsouphanh C, Willberg CB, Gordon CL, Klenerman P, Marchi E. Highton AJ, et al. Wellcome Open Res. 2019 May 9;4:78. doi: 10.12688/wellcomeopenres.15115.1. eCollection 2019. Wellcome Open Res. 2019. PMID: 31448339 Free PMC article.

2

Adenoviral vaccine induction of CD8+ T cell memory inflation: Impact of co-infection and infection order.

Lee LN, Bolinger B, Banki Z, de Lara C, Highton AJ, Colston JM, Hutchings C, Klenerman P. Lee LN, et al. Among authors: highton aj. PLoS Pathog. 2017 Dec 27;13(12):e1006782. doi: 10.1371/journal.ppat.1006782. eCollection 2017 Dec. PLoS Pathog. 2017. PMID: 29281733 Free PMC article.

3

Memory inflation following adenoviral vaccination depends on IL-21.

Gordon CL, Hutchings CL, Highton AJ, Colston JM, Provine NM, Klenerman P. Gordon CL, et al. Among authors: highton aj. Vaccine. 2018 Nov 12;36(46):7011-7016. doi: 10.1016/j.vaccine.2018.09.061. Epub 2018 Sep 29. Vaccine. 2018. PMID: 30279090 Free PMC article.

4

Divergent memory responses driven by adenoviral vectors are impacted by epitope competition.

Colston JM, Hutchings C, Chinnakannan S, Highton A, Perez-Shibayama C, Ludewig B, Klenerman P. Colston JM, et al. Eur J Immunol. 2019 Sep;49(9):1356-1363. doi: 10.1002/eji.201948143. Epub 2019 May 29. Eur J Immunol. 2019. PMID: 31106398 Free PMC article.

5

Induction and Maintenance of CX3CR1-Intermediate Peripheral Memory CD8⁺ T Cells by Persistent Viruses and Vaccines.

Gordon CL, Lee LN, Swadling L, Hutchings C, Zinser M, Highton AJ, Capone S, Folgori A, Barnes E, Klenerman P. Gordon CL, et al. Among authors: highton aj. Cell Rep. 2018 Apr 17;23(3):768-782. doi: 10.1016/j.celrep.2018.03.074. Cell Rep. 2018. PMID: 29669283 Free PMC article.

6

Human MAIT cells show metabolic quiescence with rapid glucose-dependent upregulation of granzyme B upon stimulation.

Zinser ME, Highton AJ, Kurioka A, Kronsteiner B, Hagel J, Leng T, Marchi E, Phetsouphanh C, Willberg CB, Dunachie SJ, Klenerman P. Zinser ME, et al. Among authors: highton aj. Immunol Cell Biol. 2018 Jul;96(6):666-674. doi: 10.1111/imcb.12020. Epub 2018 Mar 9. Immunol Cell Biol. 2018. PMID: 29423939 Free PMC article.

7

Elevation of CpG frequencies in influenza A genome attenuates pathogenicity but enhances host response to infection.

Gaunt E, Wise HM, Zhang H, Lee LN, Atkinson NJ, Nicol MQ, Highton AJ, Klenerman P, Beard PM, Dutia BM, Digard P, Simmonds P. Gaunt E, et al. Among authors: highton aj. Elife. 2016 Feb 16;5:e12735. doi: 10.7554/eLife.12735. Elife. 2016. PMID: 26878752 Free PMC article.

8

Chitosan gel vaccine protects against tumour growth in an intracaecal mouse model of cancer by modulating systemic immune responses.

Highton AJ, Girardin A, Bell GM, Hook SM, Kemp RA. Highton AJ, et al. BMC Immunol. 2016 Oct 18;17(1):39. doi: 10.1186/s12865-016-0178-4. BMC Immunol. 2016. PMID: 27756214 Free PMC article.

9

Chitosan hydrogel vaccine generates protective CD8 T cell memory against mouse melanoma.

Highton AJ, Kojarunchitt T, Girardin A, Hook S, Kemp RA. Highton AJ, et al. Immunol Cell Biol. 2015 Aug;93(7):634-40. doi: 10.1038/icb.2015.14. Epub 2015 Feb 24. Immunol Cell Biol. 2015. PMID: 25708538

10

Intestinal CD8⁺ T cell responses are abundantly induced early in human development but show impaired cytotoxic effector capacities.

Schreurs RRCE, Sagebiel AF, Steinert FL, Highton AJ, Klarenbeek PL, Drewniak A, Bakx R, The SML, Ribeiro CMS, Perez D, Reinshagen K, Geijtenbeek TBH, van Goudoever JB, Bunders MJ. Schreurs RRCE, et al. Among authors: highton aj. Mucosal Immunol. 2021 May;14(3):605-614. doi: 10.1038/s41385-021-00382-x. Epub 2021 Mar 26. Mucosal Immunol. 2021. PMID: 33772147 Free PMC article.

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