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Page 1
ELQ-331 as a prototype for extremely durable chemoprotection against malaria.
Smilkstein MJ, Pou S, Krollenbrock A, Bleyle LA, Dodean RA, Frueh L, Hinrichs DJ, Li Y, Martinson T, Munar MY, Winter RW, Bruzual I, Whiteside S, Nilsen A, Koop DR, Kelly JX, Kappe SHI, Wilder BK, Riscoe MK. Smilkstein MJ, et al. Malar J. 2019 Aug 27;18(1):291. doi: 10.1186/s12936-019-2921-9. Malar J. 2019. PMID: 31455339 Free PMC article.
Alkoxycarbonate Ester Prodrugs of Preclinical Drug Candidate ELQ-300 for Prophylaxis and Treatment of Malaria.
Frueh L, Li Y, Mather MW, Li Q, Pou S, Nilsen A, Winter RW, Forquer IP, Pershing AM, Xie LH, Smilkstein MJ, Caridha D, Koop DR, Campbell RF, Sciotti RJ, Kreishman-Deitrick M, Kelly JX, Vesely B, Vaidya AB, Riscoe MK. Frueh L, et al. Among authors: smilkstein mj. ACS Infect Dis. 2017 Oct 13;3(10):728-735. doi: 10.1021/acsinfecdis.7b00062. Epub 2017 Sep 27. ACS Infect Dis. 2017. PMID: 28927276 Free PMC article.
Evaluation and lead optimization of anti-malarial acridones.
Winter RW, Kelly JX, Smilkstein MJ, Dodean R, Bagby GC, Rathbun RK, Levin JI, Hinrichs D, Riscoe MK. Winter RW, et al. Among authors: smilkstein mj. Exp Parasitol. 2006 Sep;114(1):47-56. doi: 10.1016/j.exppara.2006.03.014. Epub 2006 Jul 7. Exp Parasitol. 2006. PMID: 16828746
Antimalarial quinolones: synthesis, potency, and mechanistic studies.
Winter RW, Kelly JX, Smilkstein MJ, Dodean R, Hinrichs D, Riscoe MK. Winter RW, et al. Among authors: smilkstein mj. Exp Parasitol. 2008 Apr;118(4):487-97. doi: 10.1016/j.exppara.2007.10.016. Epub 2007 Nov 7. Exp Parasitol. 2008. PMID: 18082162 Free PMC article.
Discovery of dual function acridones as a new antimalarial chemotype.
Kelly JX, Smilkstein MJ, Brun R, Wittlin S, Cooper RA, Lane KD, Janowsky A, Johnson RA, Dodean RA, Winter R, Hinrichs DJ, Riscoe MK. Kelly JX, et al. Among authors: smilkstein mj. Nature. 2009 May 14;459(7244):270-3. doi: 10.1038/nature07937. Epub 2009 Apr 8. Nature. 2009. PMID: 19357645 Free PMC article.
Optimization of endochin-like quinolones for antimalarial activity.
Winter R, Kelly JX, Smilkstein MJ, Hinrichs D, Koop DR, Riscoe MK. Winter R, et al. Among authors: smilkstein mj. Exp Parasitol. 2011 Feb;127(2):545-51. doi: 10.1016/j.exppara.2010.10.016. Epub 2010 Oct 30. Exp Parasitol. 2011. PMID: 21040724 Free PMC article.
50 results