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Synthesis and Pharmacological Evaluation of [11C]4-Methoxy-N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the δ-Subunit-Containing γ-Aminobutyric Acid Type A Receptors.
L'Estrade ET, Hansen HD, Falk-Petersen C, Haugaard A, Griem-Krey N, Jung S, Lüddens H, Schirmeister T, Erlandsson M, Ohlsson T, Knudsen GM, Herth MM, Wellendorph P, Frølund B. L'Estrade ET, et al. Among authors: luddens h. ACS Omega. 2019 May 22;4(5):8846-8851. doi: 10.1021/acsomega.9b00434. eCollection 2019 May 31. ACS Omega. 2019. PMID: 31459972 Free PMC article.
Structure-Function Evaluation of Imidazopyridine Derivatives Selective for δ-Subunit-Containing γ-Aminobutyric Acid Type A (GABAA) Receptors.
Yakoub K, Jung S, Sattler C, Damerow H, Weber J, Kretzschmann A, Cankaya AS, Piel M, Rösch F, Haugaard AS, Frølund B, Schirmeister T, Lüddens H. Yakoub K, et al. Among authors: luddens h. J Med Chem. 2018 Mar 8;61(5):1951-1968. doi: 10.1021/acs.jmedchem.7b01484. Epub 2018 Feb 26. J Med Chem. 2018. PMID: 29451785
Total synthesis and evaluation of [18F]MHMZ.
Herth MM, Debus F, Piel M, Palner M, Knudsen GM, Lüddens H, Rösch F. Herth MM, et al. Among authors: luddens h. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1515-9. doi: 10.1016/j.bmcl.2007.12.054. Epub 2007 Dec 25. Bioorg Med Chem Lett. 2008. PMID: 18187324
Furosemide interactions with brain GABAA receptors.
Korpi ER, Lüddens H. Korpi ER, et al. Among authors: luddens h. Br J Pharmacol. 1997 Mar;120(5):741-8. doi: 10.1038/sj.bjp.0700922. Br J Pharmacol. 1997. PMID: 9138676 Free PMC article.
82 results