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Reproducibility of 19 F-MR ventilation imaging in healthy volunteers.
Pippard BJ, Neal MA, Maunder AM, Hollingsworth KG, Biancardi A, Lawson RA, Fisher H, Matthews JNS, Simpson AJ, Wild JM, Thelwall PE. Pippard BJ, et al. Among authors: simpson aj. Magn Reson Med. 2021 Jun;85(6):3343-3352. doi: 10.1002/mrm.28660. Epub 2021 Jan 28. Magn Reson Med. 2021. PMID: 33507591 Free PMC article.
Target inhibition of galectin-3 by inhaled TD139 in patients with idiopathic pulmonary fibrosis.
Hirani N, MacKinnon AC, Nicol L, Ford P, Schambye H, Pedersen A, Nilsson UJ, Leffler H, Sethi T, Tantawi S, Gravelle L, Slack RJ, Mills R, Karmakar U, Humphries D, Zetterberg F, Keeling L, Paul L, Molyneaux PL, Li F, Funston W, Forrest IA, Simpson AJ, Gibbons MA, Maher TM. Hirani N, et al. Among authors: simpson aj. Eur Respir J. 2021 May 27;57(5):2002559. doi: 10.1183/13993003.02559-2020. Print 2021 May. Eur Respir J. 2021. PMID: 33214209 Free PMC article. Clinical Trial.
A human model of bilateral pulmonary vein sampling to assess the effects of one-lung ventilation on neutrophil function.
Funston W, Ruchaud-Sparagano MH, Scott J, Powell J, Cooles FAH, Shelmerdine L, McDowell C, O'Leary D, Booth KL, Clark SC, Ledingham SJ, Rostron AJ, Dark JH, Simpson AJ. Funston W, et al. Among authors: simpson aj. PLoS One. 2022 Jul 26;17(7):e0271958. doi: 10.1371/journal.pone.0271958. eCollection 2022. PLoS One. 2022. PMID: 35881612 Free PMC article.
A randomized controlled trial of peripheral blood mononuclear cell depletion in experimental human lung inflammation.
Barr LC, Brittan M, Morris AC, McAuley DF, McCormack C, Fletcher AM, Richardson H, Connell M, Patel D, Wallace WA, Rossi AG, Davidson DJ, Manson L, Turner M, Hirani N, Walsh TS, Anderson NH, Dhaliwal K, Simpson AJ. Barr LC, et al. Among authors: simpson aj. Am J Respir Crit Care Med. 2013 Aug 15;188(4):449-55. doi: 10.1164/rccm.201212-2334OC. Am J Respir Crit Care Med. 2013. PMID: 23627345 Clinical Trial.
Aspirin reduces lipopolysaccharide-induced pulmonary inflammation in human models of ARDS.
Hamid U, Krasnodembskaya A, Fitzgerald M, Shyamsundar M, Kissenpfennig A, Scott C, Lefrancais E, Looney MR, Verghis R, Scott J, Simpson AJ, McNamee J, McAuley DF, O'Kane CM. Hamid U, et al. Among authors: simpson aj. Thorax. 2017 Nov;72(11):971-980. doi: 10.1136/thoraxjnl-2016-208571. Epub 2017 Jan 12. Thorax. 2017. PMID: 28082531 Free PMC article. Clinical Trial.
FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis.
Leslie J, Millar BJ, Del Carpio Pons A, Burgoyne RA, Frost JD, Barksby BS, Luli S, Scott J, Simpson AJ, Gauldie J, Murray LA, Finch DK, Carruthers AM, Ferguson J, Sleeman MA, Rider D, Howarth R, Fox C, Oakley F, Fisher AJ, Mann DA, Borthwick LA. Leslie J, et al. Among authors: simpson aj. JCI Insight. 2020 Feb 27;5(4):e125937. doi: 10.1172/jci.insight.125937. JCI Insight. 2020. PMID: 32102985 Free PMC article.
Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID).
Wild JM, Porter JC, Molyneaux PL, George PM, Stewart I, Allen RJ, Aul R, Baillie JK, Barratt SL, Beirne P, Bianchi SM, Blaikley JF, Brooke J, Chaudhuri N, Collier G, Denneny EK, Docherty A, Fabbri L, Gibbons MA, Gleeson FV, Gooptu B, Hall IP, Hanley NA, Heightman M, Hillman TE, Johnson SR, Jones MG, Khan F, Lawson R, Mehta P, Mitchell JA, Platé M, Poinasamy K, Quint JK, Rivera-Ortega P, Semple M, Simpson AJ, Smith D, Spears M, Spencer LG, Stanel SC, Thickett DR, Thompson AAR, Walsh SL, Weatherley ND, Weeks ME, Wootton DG, Brightling CE, Chambers RC, Ho LP, Jacob J, Piper Hanley K, Wain LV, Jenkins RG. Wild JM, et al. Among authors: simpson aj. BMJ Open Respir Res. 2021 Sep;8(1):e001049. doi: 10.1136/bmjresp-2021-001049. BMJ Open Respir Res. 2021. PMID: 34556492 Free PMC article.
787 results