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Page 1
Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases.
Jurczyluk J, Munoz MA, Skinner OP, Chai RC, Ali N, Palendira U, Quinn JM, Preston A, Tangye SG, Brown AJ, Argent E, Ziegler JB, Mehr S, Rogers MJ. Jurczyluk J, et al. Among authors: rogers mj. Immunol Cell Biol. 2016 Nov;94(10):994-999. doi: 10.1038/icb.2016.58. Epub 2016 Jul 5. Immunol Cell Biol. 2016. PMID: 27377765 Free PMC article.
Defective protein prenylation is a diagnostic biomarker of mevalonate kinase deficiency.
Munoz MA, Jurczyluk J, Mehr S, Chai RC, Arts RJW, Sheu A, McMahon C, Center JR, Singh-Grewal D, Chaitow J, Campbell DE, Quinn JMW, Alexandrov K, Tnimov Z, Tangye SG, Simon A, Phan TG, Rogers MJ. Munoz MA, et al. Among authors: rogers mj. J Allergy Clin Immunol. 2017 Sep;140(3):873-875.e6. doi: 10.1016/j.jaci.2017.02.033. Epub 2017 May 10. J Allergy Clin Immunol. 2017. PMID: 28501347 Free article. No abstract available.
Lack of protein prenylation promotes NLRP3 inflammasome assembly in human monocytes.
Skinner OP, Jurczyluk J, Baker PJ, Masters SL, Rios Wilks AG, Clearwater MS, Robertson AAB, Schroder K, Mehr S, Munoz MA, Rogers MJ. Skinner OP, et al. Among authors: rogers mj. J Allergy Clin Immunol. 2019 Jun;143(6):2315-2317.e3. doi: 10.1016/j.jaci.2019.02.013. Epub 2019 Feb 21. J Allergy Clin Immunol. 2019. PMID: 30797829 Free article. No abstract available.
Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency.
Munoz MA, Skinner OP, Masle-Farquhar E, Jurczyluk J, Xiao Y, Fletcher EK, Kristianto E, Hodson MP, O'Donoghue SI, Kaur S, Brink R, Zahra DG, Deenick EK, Perry KA, Robertson AA, Mehr S, Hissaria P, Mulders-Manders CM, Simon A, Rogers MJ. Munoz MA, et al. Among authors: rogers mj. J Clin Invest. 2022 Oct 3;132(19):e160929. doi: 10.1172/JCI160929. J Clin Invest. 2022. PMID: 36189795 Free PMC article.
From vesicle to cytosol.
Rogers MJ, Munoz MA. Rogers MJ, et al. Elife. 2018 Jun 27;7:e38847. doi: 10.7554/eLife.38847. Elife. 2018. PMID: 29947329 Free PMC article.
Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer.
Junankar S, Shay G, Jurczyluk J, Ali N, Down J, Pocock N, Parker A, Nguyen A, Sun S, Kashemirov B, McKenna CE, Croucher PI, Swarbrick A, Weilbaecher K, Phan TG, Rogers MJ. Junankar S, et al. Among authors: rogers mj. Cancer Discov. 2015 Jan;5(1):35-42. doi: 10.1158/2159-8290.CD-14-0621. Epub 2014 Oct 13. Cancer Discov. 2015. PMID: 25312016 Free PMC article.
325 results